
It’s estimated around 20% of patients will discontinue their first course of anti–tumor necrosis factor-α (anti–TNF-α) and rates increase over time

It’s estimated around 20% of patients will discontinue their first course of anti–tumor necrosis factor-α (anti–TNF-α) and rates increase over time

Dennis Slamon, MD, PhD, lead investigator on the NATALEE trial of ribociclib plus hormonal therapy in hormone receptor–positive, HER2-negative early-stage breast cancer, discussed the study's broad population and potential payer reactions.

Results are based on a study of low-dose interleukin-2 (IL-2) carried out at Dana-Farber Cancer Institute.

To the authors’ knowledge, the study is the first to include a patient with essential thrombocythemia (ET) and MPL and Type 1 calreticulin gene mutations.

Abstracts presented at EULAR 2023 highlighted the impact that a mandatory switching policy had on biosimilar uptake in British Columbia, Canada, and the lack of uptake when no such policy was in place in the United States.

Surya Bhatt, MD, associate professor of medicine at University of Alabama at Birmingham, talks about a new trial in which dupilumab was used in patients with chronic obstructive pulmonary disease (COPD) with frequent exacerbations and type 2 inflammation.

The FDA has approved flotufolastat F 18 injection for positron emission tomography of prostate-specific membrane antigen–positive lesions in certain men with prostate cancer.

Although methotrexate was linked with a higher risk of anemia, it carried risks of kidney and other serious infections similar to those of biologics.

Regardless of a prior history of swallowed topical corticosteroids, dupilumab was proven to be an effective treatment in patients with eosinophilic esophagitis.

According to new estimates, the US government spent between $143 million and $314 million in 2022 inflation-adjusted dollars funding the development of tenofovir disoproxil fumarate-emtricitabine. The previous estimate was around $50 million.

Amal Agarwal, DO, MBA, chief clinical officer at Monogram Health, explains the importance of value-based agreements in dialysis care, and the issue of dialysis prevalence among low-income and marginalized communities.

The prevalence of high metabolism scores for visceral fat, especially among sensitive populations, may be associated with a heightened asthma risk, according to one study.

The study, wrote the researchers, offers insight into emerging and uncommon complications following chimeric antigen receptor (CAR) T-cell therapy.

Higher enablement was associated with being more comfortable to reconsult about persistent or worsening symptoms.

President Joe Biden has reportedly picked former North Carolina health chief Mandy Cohen, MD, MPH, as next head of the CDC; Black men were probably underdiagnosed with lung problems because of software bias; the US birthrate remains flat.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Former and current smokers showed higher mortality from early-stage non-small cell lung cancer than never smokers.

Unmet needs include both improved myasthenia gravis treatments as well as a way to monitor progression of the disease, said James F. Howard, Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill.

Deemed the “Medicare” effect, patients aged 65 years who have Medicare coverage had an increased incidence of head and neck squamous cell carcinoma (HNSCC) but were less likely to receive a late-stage diagnosis and had lower mortality rates.

The approval makes the drug Europe’s first and only interleukin (IL)-17A inhibitor approved for the condition.

There are recent reports of a potential connection between atopic dermatitis in infants and young children and early exposure to antibiotics and laxatives; however, the totality of the evidence on this link remains lacking.

Physicians should proactively ask patients what alternative therapies, if any, they are using.

The 2023 European Hematology Association (EHA) Congress, convening virtually and in Frankfurt, Germany, from June 8-11, 2023, will feature cutting-edge findings in oncology and hematology, with a special focus on incorporating patient-reported outcomes and real-world data.

At the 2023 Greater Philadelphia Business Coalition on Health annual conference, a panel of employers shared their advice on incorporating the principles of value into health benefits.

Attendees will gain insight into the future of multiple myeloma (MM) therapies and updates on pivotal clinical trials at the 2023 European Hematology Association (EHA) Congress, according to Joseph Mikhael, MD, MEd, FRCPC, FACP, chief medical officer of the International Myeloma Foundation.

New research has found the 340B program is slowing uptake of biosimilars by incentivizing use of more expensive biologics.

Jeffrey E. Lancet, MD, chair of the Department of Malignant Hematology at Moffitt Cancer Center in Tampa, Florida, gave his insight on the treatment of acute myeloid leukemia (AML) across patient groups.

Even though the number of US adults who smoke has decreased in the last decade, racial and ethnic disparities persist, and equitable interventions are needed.

The FDA approved Pfizer’s respiratory syncytial virus (RSV) vaccine Wednesday; Medicare announced plans to largely cover a new class of expensive Alzheimer drugs; more states are extending postpartum coverage under Medicaid.

Individuals with type 1 diabetes (T1D) had brain atrophy patterns equivalent to a brain age about 6 years older than their actual age.

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