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This open-label extension of the SERAPHIN trial evaluated the long-term safety and tolerability of a small daily dose of the endothelin receptor antagonist against pulmonary arterial hypertension (PAH) among patients from the original study.

Medication-at-home pharmacy is an innovative method of medication management that is vital to the success of the health care system.

A highly tailored video doctor intervention was shown to help men living with HIV achieve viral suppression, and younger and older patients achieve HIV care retention.

Understanding if local prescription patterns are influenced by guidance could help policymakers understand what is needed to further encourage a shift to asthma inhalers with less of a climate impact.

People with type 1 diabetes (T1D) who partake in fasting during Ramadan may benefit from using an advanced hybrid closed loop (AHCL) insulin pump system.

Olipudase alfa (Xenpozyme) was granted FDA approval for patients with Acid Sphingomyelinase Deficiency (ASMD); Moderna and Pfizer-BioNTech’s bivalent COVID-19 vaccines are each authorized for use as a booster dose; people with type A blood have an 18% higher risk of stroke before age 60, compared with other blood types.

Post hoc analyses of the phase 3 PEGASUS trial found that clinical and hematological improvements were associated with better patient-reported fatigue and physical function outcomes in paroxysmal nocturnal hemoglobinuria, for an overall bettering of health-related quality of life (HRQOL).

A randomized, controlled, experimental study found that a breathing exercise decreased fatigue and daytime sleepiness at the end of the fourth and eighth weeks of an intervention in patients with obstructive sleep apnea (OSA).

In this new study, investigators searched for potential predictors of melanoma thickness, with implications for treatment decisions regarding biopsy and excision margins.

US life expectancy fell by nearly a year in 2021 to 76.1 years; Pfizer’s COVID-19 pill reduced the number of hospitalizations and deaths among older adults during the Omicron surge in Israel; current smokers were found to have thicker, heavier, and weaker hearts compared with nonsmokers.

The researchers noted these improvements were seen without an increase in hyperlactatemia risk.

The findings mean it may be feasible to use adult systemic lupus nephritis (SLE) trial data to reduce the data needed for pediatric indications.

With evidence lacking on the role of inflammation in nasal polyposis (NP), this study investigated the role of 2 potential biomarkers in the nasal secretions of patients who have NP concomitant with aspirin-exacerbated respiratory disease.

People with advanced HIV initiating bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) were more likely to reach CD4 cell count levels of 200 cells/mcL or higher compared with those initiating other antiretroviral therapy (ART) regimens.

Sarah Wells Kocsis, MBA, is co-author of the Milken Institute report, “Chronic Kidney Disease: Finding a Path to Prevention, Earlier Detection, and Management.” She spoke to The American Journal of Managed Care® about the findings of the report and how they can be incorporated into care for patients with chronic kidney disease (CKD).

A cohort study found that there was an inverse association between COVID-19 infection and wearing glasses in an unadjusted analysis, although this association was not identified when adjusting for confounders.

House members in South Carolina will debate a total ban on abortions with no exceptions for rape or incest; the World Health Organization claimed that the monkeypox outbreak could be eliminated in Europe, citing slowing case counts; a study found that drinking black tea was associated with lower mortality risk.

Wayne Winegarden, PhD, of the Pacific Research Institute, explains the harm that white bagging policies cause health systems and how replacing them with new measures to boost market competition could help patients.

Patients with atopic dermatitis (AD) were not found to be at greater risk of venous thromboembolism, regardless of Janus kinase inhibitor use, according to this new meta-analysis.

A decade’s worth of retrospective data from over 1 million patients with end-stage renal disease (ESRD) undergoing dialysis showed that psoriasis may be protective against pneumonia in these patients.

This new study investigated risk factors for cardiovascular disease, including heart failure, among hospitalized patients with a recent history of methamphetamine use and priority patient populations to target.

About 1 in 7 people with systematic onset juvenile idiopathic arthritis (SJIA) will not respond to interleukin-1 or interleukin-6 inhibitors.

While cognitive behavioral therapy (CBT) is known to be effective for generalized depression and anxiety, it is only recently that research has begun exploring its specific use in diabetes, including looking at the effects on depression, anxiety, and glycemic control.

Hatim Husain, MD, associate professor in the Department of Medicine at UC San Diego, discuses must-haves for successful biomarker testing in lung cancer—in particular, non–small cell lung cancer (NSCLC)—and how the field is adapting to the targeted treatment needs of its patients.

Lack of state funding and understaffing are threatening the vaccination campaign for novel Omicron-specific booster shots; experts explore the differences between subcutaneous and intradermal delivery of monkeypox vaccines; HHS’ Office for Civil Rights is struggling to manage rising cases of cyberattacks on US health care organizations.

Having a biosimilar on formulary makes it more likely the biosimilar will be adopted. Length of time a biosimilar is on market can impact how likely it is to be added to formulary.

The real-world study adds to previous randomized controlled trial findings suggesting that shorter courses of antibiotic therapy can be sufficient for hospitalized patients with mild or moderate community-acquired pneumonia.