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Little-known drugs are now contributing to the US overdose epidemic; the Government Accountability Office finds HHS is at "High Risk Alert"; Moderna begins HIV vaccine trial.

Patients with psoriasis who experienced secukinumab secondary failure did not require switching after experiencing significant improvement of daily functioning and quality of life when given a combination rescue therapy.

Incyte has become the latest company to pull an FDA filing following Gilead and Secura Bio, which both voluntarily withdrew therapies that had been granted accelerated approval but hadn’t completed confirmatory studies for full approval.

This 9-month investigation looked into the potential for next-generation sequencing (NGS) at the point of care to increase turnaround time for biomarker testing results in advanced colorectal cancer (CRC).

The American Diabetes Association (ADA) has added a new section to their 2022 Standard of Care guidelines to assist clinicians in managing and preventing the presence of chronic kidney disease and related complications in patients with diabetes.

According to researchers, this case of a patient with spinal muscular atrophy (SMA) from Indonesia was the first to use a collaborative, multidisciplinary approach that involved obstetric, neurology, pediatric, and anesthesiology departments at a hospital.

Patients with atopic dermatitis (AD) treated with dupilumab showed reduced hospitalization rates and shorter duration of AD-related hospitalizations vs those treated with control therapies.

This new analysis among patients with stage I to III breast cancer investigated outcomes in connection with 5 care delivery variables: stage I at diagnosis, chemotherapy receipt, radiation therapy receipt, endocrine therapy initiation, and endocrine therapy continuation.

The review discussed the roles of sex, ancestry, senescence, and aging in the development of nontuberculous mycobacterial pulmonary disease.

A recent study found an association between biological rhythms affecting sleep late in pregnancy and postpartum and depressive or anxiety symptoms.

Study results showed that both the Pfizer-BioNTech and Moderna COVID-19 vaccines were safe and effective in patients with multiple myeloma, which investigators hope will improve vaccine hesitancy in the high-risk population.

In its annual Medicare Shared Savings Program (MSSP) report, CMS said the number of accountable care organizations joining increased, but a trade group said the results should have been better.

People with Parkinson disease who regularly consumed flavonoids like berries, red wine, tea, and apples had lower rates of death than people who didn’t, according to a new study.

Mepolizumab was found to reduce nasal polyp size and nasal obstruction in patients with chronic rhinosinusitis with nasal polyps regardless of the presence of potentially exacerbating comorbidities.

An analysis of data collected in 2018 shows that more work is needed to address unmet needs in episodic migraine.

Payer intervention, lack of patient savings, and confusion surrounding interchangeability are some of the many barriers standing in the way of US biosimilar uptake, with our group of panelists calling for big changes.

A study found 4 factors may correlate with increased risk of long-term COVID-19; Rhode Island joins opioid settlement against McKesson, AmerisourceBergen, and Cardinal Health; the Environmental Protection Agency announced it will station mobile equipment in Louisiana to measure air pollution.

A lack of relationships with pulmonary rehabilitation providers and provider perceptions about patient acceptance serve as limiting factors, new research shows.

Risdiplam is approved for children older than 2 months with spinal muscular atrophy (SMA); an expanded approval would include the youngest infants before they show symptoms.

Speakers at the Greater Philadelphia Business Coalition on Health (GPBCH) discussed data on lifestyles, economic trends, and presented real-life examples of obesity treatment, as well as a benefit design for obesity.

This new study of data from Kaiser Permanente Southern California compared outcomes for behavioral health referrals among patients with breast cancer between those receiving a tailored intervention or an education-only approach.

On this episode of Managed Care Cast, we speak with Michael Sun, a medical student at the Pritzker School of Medicine at the University of Chicago, who served as first author of a Health Affairs study showing that race and bias were significantly associated with negative patient descriptors in the electronic health record.

Men who have sex with men (MSM), in particular those paying for sex, need to be a priority population for targeted HIV prevention efforts in sub-Saharan Africa.

Findings from 2 studies conducted among German and US children highlight the growing incidence of type 1 diabetes (T1D) among children throughout the COVID-19 pandemic.

After analyzing past studies and classification criteria, authors found multiple factors that could be implemented into the current rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) tests for a more specific rheumatoid arthritis (RA) classification.

New research out today details the lack of price reductions seen among recently launched brand-name drugs for non–small cell lung cancer (NSCLC).

The US Preventive Services Task Force (USPSTF) had announced an update to its 2018 recommendation on screening for atrial fibrillation (AFib) for older adults.

FDA significantly restricts the use of 2 COVID-19 monoclonal antibody treatments ineffective against the Omicron variant; an expert panel advises the Israeli government to offer a fourth COVID-19 vaccine dose to adults; there was a substantial increase in visits for mental health and substance abuse among physicians with no prior history during the pandemic.