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Researchers in Poland examined the impact of vitamin D deficiency on patients with type 1 diabetes undergoing pancreas transplants.

Use of comprehensive genomic profiling in patients with advanced non–small cell lung cancer (NSCLC) was linked with significant improvements in progression-free survival and overall survival.

Michelle Afkhami, MD, from City of Hope, discusses best practices for oncology organizations to leverage molecular/genomic testing, the importance of identifying RET-positive patients early so they can receive targeted treatment, and more.

An FDA advisory panel voted 17-0 in favor of the Pfizer COVID-19 vaccine for children aged 5 to 11 years; COVID-19 pill molnupiravir to be manufactured and sold in 105 developing nations; new US COVID-19 cases dropped nearly 60% in just over a month.

The incidence of chronic liver disease is expected to sharply rise by 2030, making it important to understand the factors that influence patient outcomes.

Collaboration with community partners recognized for patient care excellence.

A new review article highlights some of the newest therapies available to treat graft-versus-host disease (GVHD), but the authors say there is insufficient data to draw broad conclusions.

Amanda Ely, CEO, introduces us to The Children's HIV Association (CHIVA) of the United Kingdom and Ireland and details how the experiences of young persons living with HIV differ from those who acquire the virus as adults.

On this episode of Managed Care Cast, we discuss senior health needs amid the pandemic and how Centerwell Senior Primary Care's holistic, team-based approach and value-based care delivery contributed to upticks in senior patient visits despite fears of COVID-19.

Pregnant women with psoriasis were found to be at increased risk of experiencing preterm birth and Cesarean delivery, with patients undergoing anti-rheumatic treatment during their first pregnancy indicated to be at significantly greater risk.

A pan-cancer reference atlas provides a framework for an immune-based patient stratification that study authors expect to be predictive for patient prognosis and immunotherapy response at an elevated level after further studies.

Results of a retrospective study found no benefits among older patients whose diabetes medication was intensified following short hospital admissions.

In patients refractory to conventional therapy, the combination resulted in a 70% reduction in a key biomarker compared with placebo.

Posters presented at AMCP Nexus 2021 evaluated the health care resource utilization (HRU) and costs associated with the chimeric antigen receptor T-cell therapies tisagenlecleucel and axicabtagene ciloleucel.

Migraineurs tend to have more anxiety when it comes to dental procedures compared with those without migraine.

Education is needed for both patients and pharmacists to ensure appropriate understanding, investigators reported at the Academy of Managed Care Pharmacy (AMCP) Nexus 2021 meeting.

The report suggests factors besides molecular profiling can be helpful in patient stratification.

The first-of-its-kind port delivery system with ranibizumab serves as the first wet age-related macular degeneration (AMD) treatment in 15 years to provide an alternative to frequent eye injections.

Local anesthesia yields superior outcomes in pregnant women with pulmonary arterial hypertension (PAH) undergoing cesarean deliveries compared with general anesthesia.

The nation's top infectious disease expert expects COVID-19 vaccination to be made available for children aged 5 to 11 years by early November; Walmart recalls aromatherapy spray due to rare and deadly bacteria contamination; COVID-19–related brain fog has been found to persist in patients for months after infection.

Patients and prescribers should be able to see the total bottom-line cost of medications along with the clinical support for why they are using them.

Many novel traits are shared through gene transfer, but scientists haven’t been able to determine why some bacteria engage in gene transfer while others do not.

An abnormal retention of mitochondria can trigger the cascade of inappropriate and harmful immune activity that is characteristic of lupus, the report said.

The issue of systemic lupus erythematosus (SLE) is particularly important in Asia, because patients there suffer from more severe disease and damage compared with patients in Western countries.

This new study from Serbia compared outcomes on oral glucose tolerance tests between women who are pregnant and those who have polycystic ovary syndrome (PCOS).

Two abstracts presented at the CHEST Annual Meeting 2021 showed that patients with narcolepsy treated with once-nightly sodium oxybate, FT218, vs placebo exhibited significant improvements in sleep latency and cataplexy.

The WISDOM study—Women Informed to Screen Depending On Measures of risk—was launched to test a personalized approach to screening compared to annual mammograms. Funmi Olopade, MD, FACP, is a professor of Medicine and Human Genetics and founding director of the Center for Clinical Cancer Genetics and Global Health at the University of Chicago Medical Center, and a co-investigator of WISDOM. She discussed how the COVID-19 pandemic actually helped increase participation in the WISDOM study and what it means for future trials.

Approximately half of patients with proliferative diabetic retinopathy exhibited long lapses in care when prescribed ranibizumab across a 5-year follow-up.