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A systematic review that aimed to find out more about how growth hormone deficiency (GHD) affects children's oral and dental development found that knowledge gaps still remain.

Clinicians are finding that there really is no basis to recommend probiotics for patients with Clostridioides difficile infection, that instead they may cause harm, said Colleen R. Kelly, MD, FACG, gastroenterologist and associate professor of medicine at The Warren Alpert Medical School of Brown University.

Real-world outcomes can differ from those seen in tightly-controlled clinical trials, so researchers wanted to examine the patterns of growth hormone treatment in a large cohort of children in Israel.

The data offer novel insights, as comparable data on the drug class is scarce despite 2 JAK inhibitors being approved for use in myelofibrosis and others showing promise.

Investigators confirmed prognostic biomarkers for premenopausal patients with hormone receptor–positive (HR+) and human epidermal growth factor receptor 2–negative (HER2–) advanced breast cancer, which could potentially be used to inform treatment decisions.

High-dose trivalent flu vaccine was associated with a reduced risk of hospitalization and emergency department visits for pneumonia or influenza in adults aged 65 and above, according to a recent study.

A new analysis of 2014-2018 data among all states plus Washington, DC, for those who have either indications for preexposure prophylaxis (PrEP) or current prescriptions for the preventive treatment, shows a widening gap in PrEP uptake, with states considered early adopters pulling ahead of those considered late adopters.

Treatment of guselkumab was found to be safe and effective in improving health-related quality-of-life (HRQOL) and skin manifestations of patients with moderate to severe psoriasis in a real-world setting.

In May, results showed that cemiplimab (Libtayo, Regeneron/Sanofi) produced significant benefits: a 31% reduction in the risk of death and a 25% reduction in the risk of disease progression.

Patients with rheumatoid arthritis (RA) who used tumor necrosis factor (TNF) inhibitors had significantly higher rates of nonmelanoma skin cancer and non-Hodgkin lymphoma.

Complications of note in patients with myeloproliferative neoplasm (MPNs) include ischemic stroke, intracerebral and subarachnoid hemorrhage, microbleeds, posterior reversible encephalopathy syndrome, and dural sinus and cerebral vein thrombosis.

A pair of surveys found that there are knowledge and practice gaps preventing earlier diagnoses of spinal muscular atrophy (SMA) in infants and toddlers.

The advisory committee voted against COVID-19 vaccine booster shots for individuals 16 years and older, but unanimously voted for booster shots for people 65 years and older or who are at high risk of severe COVID-19.

Leslie Eiland, MD, offers insights on whether use of certain technologies among patients with type 1 diabetes (T1D) will continue after the pandemic ends.

The study found that BPCI Model 3, which held postacute facilities accountable for costs of care, was not associated with payment reductions or changes in other quality and selection metrics among skilled nursing facilities.

Children who experience lower respiratory tract infections early in their lives were shown to be at significantly greater risk of developing obstructive sleep apnea in the first 5 years of life.

Results of an e-diary study compare symptoms of perimenstrual and nonperimenstrual migraine attacks among women.

At the 10th anniversary meeting of Patient-Centered Oncology Care®, sessions will cover reducing disparities in cancer care, bringing clinical trials closer to the community, and expanding the scope of what the term "precision medicine" means in cancer care.

In interviews with patients with Parkinson disease and their care partners, study authors noted that OFF periods can impair socialization, physical function, leisure activities, driving, and other means of independence.

Cost and lack of insurance are big drivers of why a physician may choose to prescribe a pegfilgrastim biosimilar over the convenient on-body device for the originator, said Kashyap Patel, MD, CEO of Carolina Blood and Cancer Care Associates.

The Department of Justice moves to stop Purdue Pharma's bankruptcy deal; Mississippi records the nation's highest COVID-19 death rate; the pandemic coincided with a rise in mass shootings.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Iksha Herr of Microsoft previews her talk on leveraging data and artificial intelligence (AI) in health care, which will be a high point of this year's Patient-Centered Oncology Care® (PCOC) conference.

Highlighting the latest ophthalmology-related news reported across MJH Life Sciences™.

A study of patients given first-line metastatic melanoma treatment showed that utilization rates were highest in patients using ipilimumab-containing therapies.

Treat-to-target has long been used in adults, but a new study finds it is warranted in pediatric cases, too.

Non-white patients with multiple sclerosis (MS), particularly African American and Hispanic American patients, were found to experience a higher level of overall disability and more severe symptoms, highlighting current disparities in this disease.

The 6-month program provides nutrition education, healthy food and recipes, and home visits.