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New strategies are currently being investigated to find out how to avoid resistance to immune checkpoint inhibitors and BRAF/MEK inhibitors.

A meta-analysis showed adding trastuzumab to chemotherapy for the treatment of early-stage, HER2-positive breast cancer could cut deaths worldwide; a researcher discusses the promise of enfortumab vedotin for advanced urothelial cancers; more research is needed in rare genomic alterations in subsets of colorectal cancer (CRC).

Updated evidence provides new insight into safety, efficacy, and challenges of deprescribing.

An overview of the latest news in Parkinson disease reported across MJH Life Sciences™.

The combination delayed disease progression for a year and a half, suggesting the treatments may be a viable option for patients not eligible for allogeneic stem cell transplantation.

Patients with chronic cough reported autonomic symptoms with substantially increased frequency and severity when compared with a healthy control population.

Use of a smartphone-based application was found to improve medication adherence and some clinical outcomes in patients managing multiple comorbidities using polypharmacy, researchers concluded.

Rajesh Rajpal, MD, chief medical officer, global head of clinical medical affairs, Johnson & Johnson Vision, speaks on the impact of screen usage for eyes and trends in eye symptom burden reported amid the pandemic.

Risk of isolated central nervous system (CNS) involvement was found to be significantly lower in patients with diffuse large B-cell lymphoma who received high-dose methotrexate vs RCHOP chemotherapy, although risk of concomitant CNS-systemic relapse rates were similar between both groups.

More than three-quarters of patients with rheumatic diseases quarantined and kept social distance during the pandemic, according to a new global survey.

Patients with nephrotic syndrome were far more likely than healthy controls to suffer end-stage kidney disease, particularly if they had focal segmental glomerulosclerosis or membranous nephropathy.

Recent research showed that patients with Medicaid are more likely than commercially insured patients to have worsened end-of-life experience and that Black patients with breast cancer fare worse than other ethnic groups when it comes COVID-19 outcomes.

Nearly 9 in 10 children given intravenous (IV) magnesium for refractory asthma ended up being admitted to the hospital, but new research suggests that may be partly due to a lack of clarity about the therapy’s safety profile.

Mortality risk stratification can identify patients with COVID-19 who are at higher risk of mortality, discharge to skilled nursing facility, and readmission, and may benefit from focused intervention strategies.

President Joe Biden pushes for measures aimed at lowering drug prices; the Supreme Court allows a vaccine mandate imposed by Indiana University to stand; heat advisories issued for almost 200 million Americans.

The meeting comes a day after the FDA approved a third dose of a COVID-19 vaccine from Pfizer-BioNTech and Moderna in people who have received organ transplants or have other conditions that have damaged their immune systems.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Jazz Pharmaceuticals’ Xywav oral solution is the first treatment to be approved for adults with idiopathic hypersomnia.

Many intrinsic and extrinsic factors hinder primary health care professionals from identifying a patient as having occupational asthma.

Results of the phase 3 REST-ON study exhibited significant improvement in patients with narcolepsy treated with once-nightly sodium oxybate, FT218, versus placebo.

A 2020 trends report from Artemetrx showed how biosimilar competition has contributed to lower average sales prices and claim percentages for originator products, suggesting that biosimilars are making a difference despite slow uptake.

The FDA is expected to authorize a third dose of the Pfizer-BioNTech and Moderna COVID-19 vaccines for immunocompromised patients; the CDC revised its COVID-19 vaccine guidance to include pregnant individuals; the FDA issued a complete response letter for the once-anticipated anemia drug roxadustat.

Telehealth utilization stabilized in May 2021 after a 3-month drop, according to FAIR Health’s Monthly Telehealth Regional Tracker. Robin Gelburd, JD, president of FAIR Health, discusses the stabilization of telehealth utilization in May 2021 after a 3-month drop.

The single-leg heel test was able to differentiate between weaker and stronger limbs in patients with multiple sclerosis (MS) and in healthy controls, suggesting that the test could prove useful for identifying impaired muscle performance.

Patients with chronic obstructive pulmonary disease (COPD) who experienced handgrip strength (HGS) weakness may be more susceptible to exacerbation, a new study shows.

Survey results underscore parents’ frustration with insurers when it comes to caring for their children with rare diseases.

In a preclinical study, researchers were able to show that their modified adeno-associated virus (AAV) vector safely delivered the chimeric antigen receptor (CAR) gene into the host cells and produced enough CAR T cells to cause effective tumor regression and elicit antitumor immunological characteristics in a mouse model of human T-cell leukemia.

Using next-generation sequencing (NGS) in clinical workflows may help address disparities in uterine cancer, which has a higher mortality for Black women.