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When drug developers were forced to conduct cardiovascular outcomes trials for SGLT2 inhibitors, they found a surprise: the drugs created for type 2 diabetes (T2D) had strong benefits for heart failure. And the same has proven true in sotagliflozin.

According to researchers, the findings suggest that receiving ibrutinib improves the activity of anti-CD19-CAR T cells.

With more than 3000 gene therapies in development, payers will have to grapple with the challenges of paying for these innovative but expensive therapies.

Patients with refractory or unexplained chronic cough are concerned about how they appear to others, and it takes them many years to get diagnosed, according to posters presented at the American Thoracic Society 2021 International Conference.

Sonia T. Oskouei, PharmD, BCMAS, DPLA, from Cardinal Health, highlights the important role that pharmacists can play in promoting uptake and expanding education efforts for biosimilars.

Stephanie Lovinsky-Desir, MD, MS, describes her research on the impact of environmental factors on respiratory health among children.

Amy Abernethy, MD, PhD, a hematologist/oncologist and palliative medicine physician, and former Principal Deputy Commissioner of the FDA, discusses new collaborations in the health economics and outcomes research (HEOR) landscape.

Children with severe atopic dermatitis, in particular, were less likely than a control group to complete education at all levels, from basic compulsory education to postgraduate education.

New guidelines recommend Americans get screened earlier for colon cancer; Johns Hopkins University will send mental health providers on security calls; Tennessee's governor signs bill limiting health care for transgender youth.

Results of a qualitative study outline widely held cost considerations regarding diabetes technology in the type 1 diabetes (T1D) community.

Priya Rajendran, BS, founder and CEO of S’moresUp and director of Product Strategy and Connected Experiences at Ford Motor Company, discusses employers’ efforts to support working moms.

During a panel at Virtual ISPOR 2021, speakers presented global perspectives of COVID-19 vaccine rollout and efforts to target vaccine-hesitant communities.

In a review, investigators concluded that physicians should use pulmonary function tests in addition to standard spirometry evaluations to better ensure that patients are appropriately being diagnosed and treated for chronic obstructive pulmonary disease (COPD).

Fernando Holguin, MD, describes the relationship between comorbid metabolic syndrome and pulmonary disease.

Lou Garrison, PhD, professor emeritus in the Department of Pharmacy at the University of Washington, explains what is needed to optimize use of health technology assessment (HTA) in the fragmented US health care system.

A series of 5 cases highlights different opportunities to incorporate selexipag into the care of patients with pulmonary arterial hypertension, potentially eliminating risks associated with parenteral prostacyclin.

May 18 is HIV Vaccine Awareness Day. Here we explore just a few of the many reasons why a vaccine that is effective at preventing the acquisition of HIV and at reducing the viral load in those currently living with HIV remains an elusive goal.

During the ATS 2021 International Conference, several studies shed new light on 2 asthma biologics.

J. Jaime Caro, MDCM, FACP, FRCPC, is chief scientist at Evidera, professor in practice at London School of Economics, and adjunct professor of medicine, epidemiology, and biostatistics at McGill University.

We want to use artificial intelligence (AI) to promote the best-case scenario in patient care, emphasized James Januzzi, MD, staff cardiologist at Massachusetts General Hospital.

Older adults who have a higher annual household income (HHI) were shown to be less likely than those with lower HHI to receive a dementia diagnosis after referral in Denmark, but more likely to receive that diagnosis earlier and at a less severe cognitive stage.

Electronic cigarettes (e-cigarettes) and heated tobacco products come with significant health risks, much as conventional cigarettes do, a study found.

The United States will ship approximately 80 million excess doses of COVID-19 vaccines abroad; Ireland's health services system could be hobbled for weeks by a ransomware attack; the FDA recalls more than 60,000 pacemakers manufactured by Abbott.

The study presented during the American College of Cardiology's 70th Scientific Session called for one group of hospitals to receive special audits and guidance aimed at improving care of patients with heart failure.

The e-cigarette or vaping product use–associated lung injury epidemic helped jumpstart the regulation of flavored e-cigarettes, said Laura Crotty Alexander, MD, ATSF.

Sessions, posters, and late-breaking trials at the American College of Cardiology’s 70th Scientific Session offer updates on vericiguat, SGLT2 inhibitors, sacubitril/valsartan, and heart failure therapies still in the pipeline.

Two posters presented at Virtual ISPOR 2021 analyzed the health care resource utilization and cost of patients with chronic obstructive pulmonary disease (COPD) with pneumonia, as well as the cost savings of treating patients with frequent or severe COPD exacerbations with a fixed-dose triple therapy.

There was consistent, and significant, benefit across all categories of ejection fraction—preserved, reduced, and midrange—but especially among those with preserved ejection fraction, noted Deepak L. Bhatt, MD, MPH, Brigham and Women’s Hospital Heart & Vascular Center.