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The discovery of a genetic signature that correlates with metastasis in prostate cancer could make it much easier for physicians and patients to choose treatment strategies.

The new report suggests that patients treated with prolonged poly-ADP-ribose polymerase inhibitors after chemotherapy may need close hematological monitoring.

While death rates related to HIV infection declined from 2010 to 2017, differences in HIV-related deaths remain among certain populations.

An eye exam paired with artificial intelligence machine learning technology may provide a novel approach to diagnose Parkinson disease in early stages.

The dearth of effective treatment options for patients with ovarian cancer not only leads to poor health outcomes, but also leads to psychological distress, according to new research.

Research behind the therapy could lead to other discoveries about heart disease as well as the aging process.

The 2019/2020 GINA guidelines recommend formoterol to produce better long-term outcomes in patients, noted Megan Althoff, MD, PhD, second-year fellow, University of Colorado, Division of Pulmonary Sciences and Critical Care Medicine.

AstraZeneca announced that its vaccine against coronavirus disease 2019 (COVID-19) could be up to 90% effective; FDA grants emergency use authorization (EUA) for antibody cocktail used against COVID-19; spotlighting shortage of specialists to operate ventilators.

A recent survey of UK Biobank participants showed that healthy sleep habits were associated with a possible lower risk of heart failure among adults, even after adjusting for several confounders.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

Authors in the Journal of Clinical Oncology discuss hypotheses on the differences in mutations and implications for treatment with PARP inhibitors.

In the FIDELIO-DKD trial researchers purposely recruited centers that had very large African American databases, said George Bakris, MD, professor of medicine and director of the American Heart Association Comprehensive Hypertension Center at the University of Chicago Medicine.

More than 1 in 4 patients with COVID-19 admitted to the hospital during the first wave of the pandemic in Finland were found to have obstructive sleep apnea, signaling a potential at-risk population.

Using DIXON, T2 mapping, and diffusion tensor imaging, the researchers obtained quantitative MRI for 31 patients with spinal muscular atrophy (SMA) types 2 and 3.

Patients with chronic obstructive pulmonary disease (COPD) may experience a difference in symptom severity depending on which risk factors they are exposed to across their lifetime.

Mounting evidence is supporting the use of poly ADP-ribose polymerase (PARP) inhibitors in prostate cancer, according to a new study.

The shift to treat patients with pediatric-onset multiple sclerosis (POMS) who are treated earlier with a wider variety of medications has led to better outcomes, according to a recent study.

A study looked at how 4 types of interventions for children with asthma could impact expenditures and utilization among Medicaid programs.

Results of the artificial intelligence (AI) model were consistent no matter which immune checkpoint inhibitor (ICI) therapy patients received, suggesting that some biomarkers are not necessarily specific to the checkpoint target.

Pfizer will submit an emergency use authorization for their coronavirus disease 2019 (COVID-19) vaccine; WHO panel recommends against remdesivir; CDC urges Americans to stay put during Thanksgiving.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

This week, the top managed care news included reports of 2 vaccines’ efficacy against coronavirus disease 2019 (COVID-19); a study finds no risk reduction in cardiac events with fish oil; calls for long-term follow-up to understand effects of lingering COVID-19.

A study looked at how 4 types of interventions for children with asthma could impact expenditures and utilization among Medicaid programs.

The mortality risk differs for the 3 endothelin receptor antagonists approved to treat pulmonary arterial hypertension (PAH) in elderly patients; however, a direct comparison in a controlled trial is still needed to confirm results.

In addition to different dosage forms of levodopa—the current standard of care for Parkinson disease—emerging trials are also examining alpha-synuclein, an abnormal protein that may be involved in the pathogenesis of the condition.

A new analysis of CREDENCE data showed that the sodium-glucose cotransporter 2 (SGLT2) inhibitor worked in advanced disease and without causing acute kidney injury.

Patients younger than 65 years represent close to 40% of deaths from metastatic breast cancer, yet their use of end-of-life (EOL) care has not been thoroughly investigated until now.

Drawing on data from 6 randomized controlled trials accounting for over 2200 patients, the researchers the researchers compared the efficacy and safety of olaparib, rucaparib, and niraparib.