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A new chimeric antigen receptor (CAR) T cell therapy may help curb the problem of frequent relapse in patients with relapsed/refractory B-cell acute lymphoblastic leukemia.

A study of patients with multiple myeloma in China found many do not have access to a caregiver and most have to travel to another city to receive treatment.

The American Journal of Managed Care® recently hosted a Peer Exchange that featured discussion among a panel of expert cardiologists and managed care decision makers regarding how cardiovascular outcome trial results are impacting the use of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in patients with heart failure and how these drugs are shaping heart failure outcomes for patients. Panelists were Nihar R. Desai, MD, MPH, assistant professor of medicine in the cardiovascular medicine section of the Yale School of Medicine and investigator in the Center for Outcomes Research and Evaluation in New Haven, Connecticut; Jaime Murillo, MD, national senior director of cardiology at UnitedHealthcare in Fort Lauderdale, Florida; and Steven Nissen, MD, chief academic officer of the Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute at the Cleveland Clinic in Cleveland, Ohio. The moderator was Neil B. Minkoff, MD, chief medical officer of Coeus Consulting Group in Sudbury, Massachusetts.

An editor from The American Journal of Managed Care® spoke with Darren K. McGuire, MD, MHSc, to discuss the impact of the results of cardiovascular outcome trials on the use of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in patients with heart failure in real-world clinical practice. McGuire is professor of medicine, director of the cardiology clinical trials unit, and director of the Parkland Hospital and Health System outpatient cardiology clinics at the University of Texas Southwestern Medical Center in Dallas.

A study out of Scotland has linked levels of 2 short-chain fatty acids in female patients with early-stage breast cancer to pathological complete response (pCR) to neoadjuvant chemotherapy.

As cancer care providers, aligning care with each patient's personal goals is a key point to be further discussed at this year's Patient-Centered Oncology Care® 2020 virtual conference.

The high rate of persistence found in the real-world study indicates dupilumab was well tolerated and patients were satisfied with its effectiveness.

More than half of the patients in this study, with either non–small or small cell lung cancer, experienced changes in their treatment plan during the coronavirus disease 2019 pandemic this spring.

In individuals suffering from chronic and episodic migraine, a preliminary study shows exposure to green light therapy significantly reduced headache days and improved both intensity and duration of headache attacks.

People with Parkinson disease (PD) were found to be more likely than those without the condition to have orthostatic hypotension, a sudden drop in blood pressure upon standing that can exacerbate the risk of falling.

The study confirms previous observations of different trajectories between the progression of the 2 spinal muscular atrophy subtypes, the researchers said.

Researchers find that 32% of examined contact sport athletes who had developed chronic traumatic encephalopathy experienced sleep symptoms characteristic of rapid eye movement sleep behavior disorder, which only affect an estimated 1% of the general population.

Both patients with early and established psoriatic arthritis (PsA) have similar improvements in general health and mental well-being after treatment with secukinumab.

For this year's Patient-Centered Oncology Care® 2020 virtual conference, the discussion on clinical pathways will address how to optimize new data on innovations within oncology.

Widely accepted guidelines that patients with cardiac diseases still get at least 150 minutes of exercise each week may need to adjust their accelerometer data for patients with heart failure.

A cost-saving provision made possible by the recent COVID-19 relief CARES Act now allows Americans to leverage pre-tax funds from their flexible spending arrangements [FSAs] or health savings accounts [HSAs] to purchase over-the-counter medicines and menstrual care products.

Among individuals hospitalized with coronavirus disease 2019 (COVID-19) in Suizhou, China, the proportion of patients who wore glasses for extended daily periods was smaller than the general population.

A systematic review concluded that a correlation between magnesium deficiency and headaches exists, while magnesium deficiency may be an independent risk factor for migraine.

Wearing masks may not stop the spread of coronavirus disease 2019 (COVID-19) via restaurants; COVID-19 trials need more Black participants; the pandemic has disproportionately disrupted HIV care services in the South.

At this year's Patient-Centered Oncology Care® 2020 virtual conference, purported lack of incentives, transparency in the supply chain of pharmacy benefit manager (PBM) operations, and the overall health care system will be discussed.

As smoke from West Coast wildfires threatens to worsen outdoor air quality across the country, concerns of indoor air quality are mounting following reports on how insufficient ventilation systems facilitate aerosol spread of COVID-19.

We should look forward to a safe, effective vaccine for coronavirus disease 2019 (COVID-19) but not expect it to be the ultimate panacea.

Sickle cell disease is a costly disease for patients, but when those patients suffer from end-organ damage, the costs jump significantly.

Ibrutinib can lead to side effects, causing some physicians to consider reducing the dose or temporarily halting therapy, but that risks disease flares, a new study finds.

NIH investigates a serious side effect from a COVID-19 vaccine trial; a report says the pandemic has erased 25 years' worth of global health gains; the US seeks to extend a ban on global health aid for foreign organizations that provide or promote abortions.

At Ochsner Health, the largest nonprofit academic health care system in Louisiana, providers are leveraging the system’s Connected Maternity Online Monitoring (MOM) digital medicine program to minimize expectant mothers’ risks of contracting COVID-19.

A review discusses what immunotherapies are currently being evaluated to target α-synuclein, an abnormal protein suggested to have a central role in the pathogenesis of PD.

During a featured discussion at this year’s Patient-Centered Oncology Care® 2020 virtual meeting, innovations and subsequent challenges in employing these advances within the treatment of cancer will be addressed.