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Alexey Aleshin, MD, senior medical director of Oncology at biotech giant Natera, said that attention on finding biomarkers for metastatic reoccurrence needs to be directed at women with a high risk of this happening.

Starting in 2 weeks, allocation of coronavirus disease 2019 (COVID-19) vaccines will be based on the percentage of doses each state has successfully administered thus far and the number of residents aged 65 or over, according to HHS.

Emerging research into natural killer cells has shown promise, but the findings are complicated by the heterogeneity of multiple myeloma (MM).

Erenumab treatment has been associated with reductions in migraine frequency and improvements in health-related quality of life that were maintained for at least 5 years, according to the results of an open-label treatment phase of a recent study.

FDA accepts for priority review a Biologics License Application for V114, Merck's investigational 15-valent pneumococcal conjugate vaccine; bluebird bio will be split into 2 publicly traded drug companies; a new variant of coronavirus is reported in Japan.

Study results, published in JAMA Ophthalmology, showed the Home Acuity Test can be used to measure visual acuity by telephone for a wide range of outpatients with diverse conditions under the care of an ophthalmologist.

Defective metabolism of levodopa in the brain was associated with a decline in the drug's efficacy over time and the adverse effect of dyskinesia among patients with Parkinson disease.

A more aggressive tumor microenvironment may be to blame for the exaggerated inflammatory response more often seen in Black women with breast cancer compared with White women.

A new American Diabetes Association (ADA) survey highlights how the coronavirus disease 2019 (COVID-19) pandemic took a toll on the population with diabetes, which is one of the most prevalent preexisting conditions in America.

Data on patients with migraine who stopped erenumab treatment show that over half of patients had an early disease worsening while the remaining patients maintained their responder status during weeks 1 through 4 post treatment.

The incoming Biden administration announces plans to rapidly release most available vaccine doses against coronavirus disease 2019; the Trump administration approves the first Medicaid block grant in Tennessee; pharmaceutical executives and trade groups condemn last week’s pro-Trump riots on Capitol Hill.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

New study findings may pave the way for research into the prognostic value of white matter lesions in heart failure and the impact that HF therapies have on them.

Daniel F. Hayes, MD, offers definitions and an algorithm for clinicians to define clinical utility.

Among patients who have chronic obstructive pulmonary disease (COPD), the pathophysiology for disturbed sleep consists of physiological changes, ventilatory disturbances, and inflammation.

Changes in circulating tumor DNA (ctDNA) are indicative of treatment response in early-stage breast cancer, pointed out Alexey Aleshin, MD, senior medical director of Oncology at biotech giant Natera.

A recent study explored how patients with Parkinson disease who suffer from constipation are more likely to have other nonmotor symptoms than patients without constipation.

The findings could lead to a precision medicine approach to prostate cancer screening.

A study links the size of cysts associated with endometriosis with coexistent ovarian cancer.

Amid speculation that total blood counts may be associated with heart failure prognosis, researchers find that higher levels of platelet distribution width could be used to predict a worse prognosis for heart failure.

The FDA decision on dapaglifozin for CKD is expected in the second quarter of 2021.

A review explored the potential role of eosinophils and their mediators in the pathophysiology of chronic rhinosinusitis (CRS) subtypes.

The American Hospital Association (AHA) asks HHS Secretary Alex Azar to expedite the rollout of coronavirus disease 2019 vaccines; CDC data show accelerated cardiac aging among cancer survivors; a study examines new targets for reducing adolescent access to opioids.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Researchers conducting a large epigenome-wide association study identified several methylation sites associated with hereditary transthyretin amyloidosis (hATTR), a rare, life-threatening disorder caused by amyloidogenic coding mutations in the TTR gene.

This week, the top managed care news included FDA advising against changes to vaccine dose schedules; drop in mammography screenings during the first months of the pandemic; first anti-TIGIT therapy granted Breakthrough Therapy designation by the FDA.

Patients with psoriasis may be more likely to have additional autoimmune disorders, including vitiligo, diabetes, autoimmune thyroiditis, rheumatoid arthritis, and inflammatory bowel disease.