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Chimeric antigen receptor (CAR) T-cell therapy has been shown to improve health-related quality of life in patients with relapsed/refractory diffuse large B-cell lymphoma (LBCL). Currently, CAR T-cell therapies are primarily administered in inpatient settings. In a study published in JAMA Network Open, researchers found CAR T-cell therapy administered to patients with relapsed or refractory LBCL in outpatient settings was associated with lower estimated overall costs.

Online systems, including telehealth, are imperative to maintaining optimal care for patients with multiple sclerosis (MS) during the coronavirus disease 2019 (COVID-19) pandemic, said June Halper, MSN, APN-C, MSCN, FAAN, chief executive officer, Consortium of Multiple Sclerosis Centers, in an interview with The American Journal of Managed Care® (AJMC®).

A number of advances have been made in recent years in our understanding of the genetics of psoriatic diseases and psoriatic arthritis specifically. However, those advances have yet to translate into clinically meaningful insights.

A new study based on treatment of patients with chronic lymphocytic leukemia (CLL) in mostly community settings challenges earlier findings about the superiority of a common therapeutic approach and also makes a strong case for ibrutinib.

Chronic obstructive pulmonary disease (COPD) is not an independent risk factor for metabolic disorders, according to a recent report.

In a set of updated guidelines issued for general neurologists managing patients with Parkinson disease (PD), researchers note the significance of efficient communication with members of a healthcare team specialized in movement disorders as they may assist in identifying and resolving common issues, especially among those with advanced PD.

A new survey found around 20% of cancer survivors are reluctant to switch jobs for fear of losing health insurance; the coronavirus disease 2019 (COVID-19) pandemic is disrupting anti-malaria campaigns in Africa; pregnant women and newborns may face pandemic complications at birth.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

This week, the top managed care news included HHS' plans to allocate the remaining $70 billion in COVID-19 funding to providers; an analysis finding aggressive social distancing measures economically justified; highlights from this week's virtual Community Oncology Conference.

Compared with conventional methods, novel polysomnography parameters better describe how the severity of oxygen desaturation during sleep affects daytime alertness in patients with obstructive sleep apnea (OSA), according to study findings.

A new poll conducted by the Kaiser Family Foundation shows a majority of Americans fear the worst of the coronavirus disease 2019 (COVID-19) pandemic is yet to come; reports of blood clots in patients with COVID-19 raise concerns; Veterans' Affairs medical facilities are struggling to cope with the pandemic.

Implanting intraocular lenses (IOLs) after cataract surgery in infants is neither beneficial nor detrimental to long-term visual outcomes, according to a study published in JAMA Ophthalmology.

HHS will divide the remaining $70 billion of financial assistance included in the bipartisan CARES Act to providers and hospitals by 4 tranches, saying the money would also be used to provide care for the uninsured who are ill with coronavirus disease 2019.

In the United States, heart failure affects a patient population of over 6.5 million. Through medication management, transportation, and emotional support, among the many tasks they assist with, these patients’ caregivers provide services valued at $7.9 billion annually.

The FDA granted accelerated approval to Immunomedics’ Trodelvy (sacituzumab govitecan-hziy) as the first antibody-drug conjugate that targets the Trop-2 antigen. Trodelvy is indicated for treatment of relapsed or refractory metastatic triple-negative breast cancer (TNBC) that has spread to other parts of the body.

Researchers found that signs of autoimmunity can appear in Parkinson disease years before an official diagnosis, which may allow for heightened detection before symptom onset and greater preventive measures to slow disease progression.

Some rural communities are only now seeing an uptick in coronavirus disease 2019 cases; lifesaving organ donations have seen precipitous drops as of late; the current social distancing measure of 6 feet may not apply in all cases.

As some states move to eschew social distancing recommendations by beginning plans to reopen businesses amid the coronavirus disease 2019 pandemic, a group of economists highlight in a recent study that the potential benefits of social distancing in saving lives far outweigh the projected damage to the economy.

Individuals with type 2 diabetes (T2D) who underwent Roux-en-Y gastric bypass exhibited greater weight loss, a slightly higher T2D remission rate, less T2D relapse, and better long-term glycemic control compared with those who had sleeve gastrectomy, according to a study published in JAMA Surgery.

Visual impairment may be a risk factor for dementia, according to a study published in JAMA Ophthalmology in which researchers compared the likelihood of incident dementia or mild cognitive impairment among women with and without baseline visual impairment.

Cognitive impairment is a well-documented adverse effect of treatment from breast cancer. Complications from it can appear soon after treatment has begun or far down the road.

Nearly 5 in 10 individuals in the United States—150 million Americans—live where pollution levels are often too dangerous to breathe, according to the American Lung Association’s annual State of the Air Report, released today. Poor air quality has been linked to higher rates of chronic diseases, comorbidities, and poor health outcomes. Several studies suggest poor air quality is a contributing factor to the prevalence of coronavirus disease 2019 (COVID-10) in some communities.

CMS will allow clinicians who participate in the Quality Payment Program to earn credit in the Merit-based Incentive Payment System (MIPS) for participation in a coronavirus disease 2019 (COVID-19) clinical trial and reporting clinical information; President Trump announced via Twitter that he would sign an executive order to temporarily suspend immigration; findings from antibody testing in Los Angeles indicate that more people have been infected with COVID-19 than initially confirmed.

Structural volume and connectivity changes of the cerebellum may impact headache persistence in patients with high-frequency migraine (HFM), according to a study published in The Journal of Headache and Pain.

Nearly 7 in 10 employees indicated in a survey by mental health provider Ginger that the coronavirus disease 2019 (COVID-19) pandemic is the most stressful time of their entire professional career, which has aligned with stark increases in new prescriptions of antidepressant, antianxiety, and anti-insomnia medications.

Chlamydia, gonorrhea, syphilis, and trichomoniasis are 4 sexually transmitted infections (STI) that have seen sharp increases in occurrence over the past 10 years. Their combined overall rate rose 31% between 2013 and 2017 and correlate with a lower overall HIV testing rate among adolescents.

The FDA Friday approved pemigatinib for adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement.

Which pulmonary manifestations were present among patients with connective tissue disorder?