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The importance of sleep is magnified for patients with Alzheimer disease (AD), who commonly experience sleep disturbances due to changes in their neurotransmitter systems. However, the impact of AD and other dementias on sleep is also seen among caregivers of patients with dementia.

As rising drug costs continue to take up a larger portion of the total cost of care, practices in the Oncology Care Model find themselves in control of a shrinking portion of total costs, according to anecdotes from an academic medical center and a community-based practice during the National Comprehensive Cancer Network’s Policy Summit held September 12 in Washington, DC.

Sessions and posters from the 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis discussed various ways to measure patient-reported outcomes in multiple sclerosis.

The Health Care Cost Institute (HCCI) Tuesday released their final Healthy Marketplace Index, which also showed that 69% of markets studied showed an increase in concentration.

The FDA grants fast track designation of AstraZeneca's dapagliflozin; California to conduct public awareness campaign against vaping; no new US measles cases.

Researchers found that post-chemotherapy minimal residual disease (MRD) subtypes were associated with a pattern of failure and time to failure.

Oncologists may be able to use circulating tumor DNA (ctDNA) to guide treatment decisions and predict which patients will have disease recurrence, according to 2 studies in JAMA Oncology.

Amgen recently announced early phase 3 CANDOR study data, showing the triple-drug combination of carfilzomib (Kyprolis), along with dexamethasone and daratumumab (Darzalex, sold by Janssen), met its primary end point of progression-free survival in patients with relapsed or refractory multiple myeloma, with a 37% reduction in the risk of progression or death.

The leaders of the Energy and Commerce Committee sent letters to 3 private equity firms seeking information. The committee has already unanimously voted out the No Surprises Act to protect consumers.

The researchers found that HIV significantly increases the risk of atrial fibrillation—a leading cause of stroke—at the same rate as or higher than known risk factors, including diabetes and hypertension.

Oxycontin manufacturer Purdue Pharma files for bankruptcy; the rise in uninsured immigrants may be associated with fear of the Trump administration's crackdown on immigrants; an investigation has found that some cannabidiol (CBD) products are being spiked in Maryland.

Up to 12% of pharmacy spending may be on high-cost, low-value drugs that can be removed from formularies.

Using national electronic health record information on more than 40 million patients over a 20-year period, researchers have found that the proportion of Americans older than 18 years who have had a prior HIV test could be as low as 6.4%. However, they noted several limitations of their analysis.

Intensive lifestyle intervention focusing on weight loss may reduce cardiovascular events in selected type 2 diabetes patients yet have a detrimental treatment effect in some, according to recent research.

Home initiation of chronic noninvasive ventilation in patients with chronic obstructive pulmonary disease (COPD) with chronic hypercapnic respiratory failure was shown to be as safe as in-hospital initiation, and reduced costs by more than 50%, according to a new study.

A study investigating the functional connectivity of the praxis network in patients in the early stages of Parkinson’s disease (PD) found that dopaminergic therapy may normalize praxis abilities and related praxis networks during the early stages of the disease by facilitating the propagation of long-term representations of object-related actions to motor execution areas.

A recent study looked at the role of the cerebellum and brainstem in migraine pain.

Despite growing interest in addressing social determinants of health and recent research into interventions that address food insecurity, there are only a small number of low-quality studies in the area.

The research found that aerobic exercise for 30 to 45 minutes for 3 times a week had an effect similar to that of several conventional Parkinson drugs in patients with mild severity.

The clinical significance of minimal residual disease (MRD) status was recently highlighted in The American Journal of Managed Care®’s Peer Exchange series “A Review of the Treatment for Multiple Myeloma.” During the series, key opinion leaders discussed the clinical implications and significance of MRD testing in patients with multiple myeloma.

The ability to provide long-acting reversible contraceptive to adolescents seeking birth control on the same day as their clinic visit is linked with potentially significant cost savings for insurance providers, according to a study.

The September issue of The American Journal of Managed Care® (AJMC®) featured research on federal healthcare reform that detailed innovative ideas in Medicare, Medicaid, and the Veterans Affairs health system. Here are 5 findings from research published in the issue.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

A CRISPR therapy for a man with HIV has resulted in no side effects but is ineffective; nursing facilities are a breeding ground for drug-resistant germs; Walmart has opened its first “Walmart Health” center, offering a variety of health services.

This week, the top managed care news included a report showing the US uninsured rate rose in 2018; the Trump administration indicating it will ban all flavors of e-cigarettes except for tobacco; new research showing the prevalence of hemophilia is 3 times larger than originally believed.

As an FDA advisory committee prepares to meet Friday to discuss an application from Aimmune Therapeutics for AR101, its peanut oral immunotherapy (OIT) product, results of a different phase 2 study were released late Thursday indicating that those with allergies to the legume would have to continue treatment in order to avoid reactions.

Napping during the day 1 or 2 times weekly may lower risk of heart attack and stroke, but no association was found with the duration or greater frequency of naps, according to a new study.

As orphan drugs account for an increasing share of drugs approved, they are driving up the cost of drug launches and drug prices. In a new paper, America's Health Insurance Plans analyzes these rising costs and the use of orphan drugs and asserts that policy makers need to revisit the Orphan Drug Act.