Clinical

Researchers found indicators that increased the risk of thromboembolic events in patients with paroxysmal nocturnal hemoglobinuria (PNH).

Experts discuss the significance of treatment selection in patients with driver mutations.

No significant differences in resistance were observed against participants with acne vulgaris (AV) against 7 antibiotics.

Lisa Rometty, CEO at Zerigo Health, discusses digital health innovations, strategies, and partnerships to improve the lives of patients living with chronic skin conditions.

RSV diagnosis can lead to an array of financial complications.

However, women with type 2 diabetes and polycystic ovary syndrome (PCOS) in pregnancy did not have worse neonatal outcomes, a study found.

The authors use surgical resident assignment as an instrumental variable for discharge opioid prescribing and estimate the impact of discharge opioid supply on subsequent use.

A panel of medical experts begin a discussion addressing the incidence and prevalence of chronic kidney disease (CKD).

Dr Haumschild drives a conversation regarding CKD treatment in the presence comorbidities such as cardiovascular disease and type 2 diabetes.

Researchers noted that the relationships between smoking, chronic obstructive pulmonary disease (COPD), and depression must be recognized to effectively manage the complicated care needs for this patient population.

Osimertinib administered in addition to chemotherapy showed more progression-free survival (PFS) benefit than just osimertinib in patients with epidermal growth factor receptor–mutated (EGFRm) advanced non–small cell lung cancer (NSCLC).

Results from ATLANTE/ENGOT-ov29 show that atezolizumab did not significantly improve progression-free survival (PFS) compared with placebo plus bevacizumab for patients with platinum-sensitive ovarian cancer.

Telehealth visits were just as effective as in-person visits at managing patients initiating apremilast.

Automated ventilatory burden can effectively assess obstructive sleep apnea (OSA) severity, estimate cardiovascular (CVD) mortality, and may present a promising alternative to apnea-hypopnea index (AHI).

Study results suggest the greatest risk for Clostridioides difficile infection was observed with use of clindamycin while the lowest risk was observed with doxycycline and minocycline.

Patients with advanced or metastatic non–small cell lung cancer (NSCLC) were able to specify a 1-point threshold when describing meaningful symptom change, for better or worse, that helped illustrate their symptom experience.

Perampanel was found effective and safe for prolonged use in children with epilepsy, according to one study.

FDA approves updated COVID-19 booster vaccines; low donor turnout and climate disasters result in a national blood shortage; minority patients discouraged by lack of doctor diversity.

Ryan Haumschild, PharmD, MS, MBA, director of pharmacy at Emory Winship Cancer Institute, discusses treatment options available to patients with rare diseases, as well as the challenges these patients and their pharmacists face in accessing these treatments.

As patients’ atopic dermatitis (AD) worsens, the risk of inflammatory bowel disease, Crohn disease, and ulcerative colitis increases.

There are multiple treatment options becoming available for diffuse large B-cell lymphoma, but more work needs to be done to understand their efficacy and in what lines of therapy they should be used.

Boys who smoke in their early teens increase risk of their future children developing asthma, obesity, and low lung function, a study suggests.

New research suggests an association between gestational diabetes history and mortality over 30 years, regardless of whether it manifests into type 2 diabetes.

The LEAP-017 trial results presented at ESMO GI 2023 are explored by Dr Marshall.

Discussion on treatment algorithms as well as the impact of sebum in acne patients.

An overview on adverse effects for topical clascoterone, minocycline, and trifarotene

The highest proportions of patients with severe ocular impairment at baseline showed greater improvements in symptom severity on ravulizumab in comparison with placebo after 26 weeks.

New research suggests conventional fractionated and hypofractionated proton postmastectomy radiotherapy (PMRT) yield similar tolerability and complication rates for patients following mastectomy.

A study found acute myeloid leukemia (AML) salvage therapy was independently associated with early mortality compared with frontline therapy, suggesting that algorithms measuring quality of care should incorporate risk mortality indices that factor in disease characteristics and treatment status.

Two abstracts presented at the 2023 International Epilepsy Congress evaluated early electroencephalography (EEG) monitoring in children with seizures and encephalopathy.