Opinion|Videos|September 10, 2025
Analyzing the Safety Data of JAK Inhibitors
Key Takeaways
- Alopecia areata is a chronic autoimmune disorder causing non-scarring hair loss due to immune system attacks on hair follicles.
- Breakdown of immune privilege in hair follicles leads to infiltration by cytotoxic T cells, particularly CD8+ T cells.
Panelists discuss the key safety data observed with each of the three Janus kinase (JAK) inhibitors for alopecia areata (AA), highlighting potential adverse effects and how these impact clinical decision-making.
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Episodes in this series
Video content above is prompted by the following:
- Mostaghimi: Please discuss key safety data seen with each of the 3 JAK inhibitors.
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