Opinion|Videos|August 20, 2025

Adherence to Alopecia Areata Therapies

Name: Adherence to Alopecia Areata Therapies
Uploaded: 2025-08-20T12:00:00.000Z
Duration: pt4m14s
Description: Adherence to Alopecia Areata Therapies

Author(s)Ryan Haumschild, PharmD, MS, MBA, Amy McMichael, MD , Benjamin Ungar, MD

Key Takeaways

Alopecia areata is a chronic autoimmune disorder causing non-scarring hair loss due to immune system attacks on hair follicles.
Breakdown of immune privilege in hair follicles leads to infiltration by cytotoxic T cells, particularly CD8+ T cells.
Inflammatory cytokines like IFN-γ and TNF-α are key contributors to immune-mediated hair follicle destruction.
The chronicity of alopecia areata is linked to persistent immune dysregulation and genetic predisposition.

Panelists discuss how adherence to conventional therapies for alopecia areata (AA) can be challenging, with adverse effects often impacting patient compliance, and how the most common cause of nonadherence is the lack of visible improvement or perceived efficacy.

Video content above is prompted by the following:

Mostaghimi: How would you rate the overall adherence to conventional therapies in patients being treated for AA?
1. Do the adverse effects of a patient's treatment typically affect adherence?
2. What is the most common cause for nonadherence in patients with AA?

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Adherence to Alopecia Areata Therapies

Key Takeaways

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