From Silos to Holistic Care: Implementing Early Detection in CRM Syndrome

In this episode, ‘From Silos to Holistic Care: Implementing Early Detection in CRM Syndrome,’ the expert nephrologist explored the following questions:

What role do non-invasive tests, such as uACR and eGFR, play in scalable, system-wide screening programs?

How can cross-disease progression awareness improve identification of at-risk patients?

Why is it important to educate and empower primary care physicians in early detection strategies with uACR and eGFR screening?

The panelist examined the critical need to identify high-risk populations, particularly those with diabetes and hypertension, through automated electronic health record (EHR) triggers and policy-level quality incentives. Manisha Jhamb discussed the "renaissance period" in nephrology, noting that the advent of new cardiorenal protective therapeutics makes early identification essential for changing disease trajectories. She emphasized shifting away from siloed disease management toward a holistic approach where all members of the care team—including cardiologists and endocrinologists—feel confident ordering appropriate screening tests. The conversation also touched on the "valley of death" in implementation science, highlighting the 17-year gap between clinical research and standard practice that health systems must work to close.

The next episode in this series, ‘Moving Upstream: Health System Innovations in Early CKD Detection,’ features the panelist advancing their conversation on cardio-renal-metabolic syndrome and focusing on patient engagement strategies and the implementation of value-based population health models.