COPD

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Type 2 Inflammation: A Common Theme Among Several Chronic Diseases

Learn about the multifaceted aspects of type 2 inflammatory diseases, including impact on quality of life; the role of biomarkers in diagnosis and treatment selection; and unmet needs in clinical management.

Type 2 Inflammation: A Common Theme Among Several Chronic Diseases

CME Content


While pulmonary rehabilitation (PR) is an evidence-based and cost-effective treatment for people with chronic obstructive pulmonary disease (COPD), uptake of and compliance with this intervention has been poor. For patients who decline PR, inspiratory muscle training (IMT), which involves strengthening the inspiratory muscles by increasing their workload, may be an option, particularly as it can be performed in the home instead of in a clinic.

Using bronchodilators early on in patients with chronic obstructive pulmonary disease (COPD) is increasingly understood to be an important therapeutic intervention to improve quality of life, inhibit disease progression, and allow for greater physical activity. One recent paper sought to compare 2 treatment options with respect to their impact on pulmonary function, health-related quality of life, and physical activity: twice-daily inhalation therapy with aclidinium and once-daily inhalation therapy with tiotropium.

A recent study used a cross-sectional analysis of a large cohort of patients with atrial fibrillation (AF) to investigate the relationship between chronic obstructive pulmonary disease (COPD) and AF to identify mediators of increased vascular risk; they found that the risk of cardiovascular complications is higher for patients with AF who also have COPD than it is for patients without COPD.

The prevalence of chronic obstructive pulmonary disease (COPD) was nearly 50% higher among patients with arthritis compared with those without arthritis, even after adjusting for sociodemographic characteristics, risk behaviors, frequent distress, and asthma status.

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