COPD

Although arterial stiffness in patients with chronic obstructive pulmonary disease (COPD) increases over time, a greater annual increase may be associated with the severity of emphysema, systemic inflammation, and dyslipidemia, according to study findings.

In study findings demonstrating differentially expressed genes (DEGs) among healthy patients and those with chronic obstructive pulmonary disease (COPD), researchers show that key genes CYP1B1, VEGFA, BCL2, and CDKN1A may have significance in analyzing the development and progression of COPD.

Extracting lung function measurements from electronic health record (EHR) data through an automated tool, such as Microsoft SQL Server’s full-text search feature, may be efficient and improve the number of values available, leading to improved phenotyping of patients with COPD, according to study findings.

Researchers discuss optimal approaches to treating hypertension in patients with COPD, with a given patient’s underlying lung function and any coexisting conditions highlighted as important factors of drug therapy choice.

Tracheobronchial colonization by pseudomonas aeruginosa was shown to increase the mortality risk of outpatients with chronic obstructive plumonary disease (COPD) by 47%, according to study results.

For those with mild to moderate chronic obstructive pulmonary disease (COPD), researchers suggest that antibiotic stewardship focus on reducing and optimizing antibiotic use in patients with severe COPD who have a significant risk of drug resistance, according to study findings.

Specific cancer drugs were shown to inhibit cell signaling processes that contribute to neutrophils, immune cells that cause inflammation to the lungs and serve as the main driver of lung damage in patients with chronic obstructive pulmonary disease (COPD), according to study findings.

Maximal inspiratory pressure (MIP) is associated with leg muscle strength in patients with chronic obstructive pulmonary disease (COPD), but not with walking distance or symptoms exhibited by the same patients, according to a recent study.