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Talazoparib in combination with enzalutamide showed a 55% reduction in the risk of disease progression or death for patients with metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene mutations in the phase 3 TALAPRO-2 trial.

White House executives met with opioid overdose reversal drug company representatives Tuesday in an attempt to resolve concerns around the drugs’ costs; a national panel of officials recommends that most adults be screened for depression and anxiety, but not suicide; New York passed a law to protect abortion providers who send abortion pills to states with bans.

In this interview from SLEEP 2023, Andrew McHill, PhD, of Oregon Health and Science University (OHSU), explains the importance of individualizing sleep hygiene recommendations.

Improving access to diabetes technology so that everyone can benefit is a top priority, said David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital.

Initiating targeted therapy for eligible patients with advanced non–small cell lung cancer (NSCLC) was found to improve outcomes, even when patients were started on nontargeted therapy but switched in a timely manner.

Certain sleep difficulties present in the transition from childhood to adolescence might be associated with psychopathology symptoms.

Biosimilars are starting to make a significant impact in overall drug spending, which is what they are designed to do, said Scott Soefje, PharmD, director of pharmacy cancer care at Mayo Clinic.

Higher levels of fractional exhaled nitric oxide (FeNO) were found in patients with eosinophilic esophagitis (EoE) and might be able to provide a measurement of clinical treatment response in a subset of these patients.

Social risk factors, such as patient characteristics and where they live, informed the severity of microbial keratitis in a sample of patients.

The burden of respiratory syncytial virus (RSV) and the effect of vaccines could be affected by underestimation of RSV in older adults.

Mandy Cohen, MD, MPH, will take over the CDC; abortion activists acknowledge 1 year without Roe v Wade; Bristol Myers Squibb (BMS) challenges Medicare’s drug price negotiation program.

Adolescents can substantially increase sleep duration by advancing their bedtime, study shows.

Investigators found important differences that may help clinicians better understand how to manage toxicities associated with the therapy.

An analysis of Medicaid data from adults in Alabama suggests just more than 50% of patients fail to get ambulatory follow-up care within the recommended 14-day window following a first-time heart failure hospitalization.

Guidelines for written eczema action plans need to be reviewed for effectiveness before more WAPs are created.

The findings, which suggest that axicabtagene ciloleucel (axi-cel) may be a good option for a patient group often deemed ineligible for other curative-intent therapy, come from a planned subgroup analysis from the ZUMA-7 trial.

These patients experienced overall improvements in objective health outcomes during the crisis compared with before the health emergency.

Scientists have found a new therapy for the severe inflammatory skin disorder.

At a median follow-up of 10.7 months, the overall response rate was 63.1%.

The risk of CDI increased at a tertiary hospital, but not at the 2 community hospitals included in the study.

Future myasthenia gravis therapies have different mechanisms of action than current treatments, said James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill.

There was no difference in second primary cancer risk among older adult male patients treated with intensity-modulated radiotherapy (IMRT) vs 3-dimensional conformal radiation therapy for prostate cancer.

An evaluation of a same-day HIV pre-exposure prophylaxis (PrEP) program in Jackson, Mississippi, showed that most individuals given a same-day prescription either never started PrEP or stopped use within 3 months.

The phase 3 LUNAR trial evaluating tumor treating fields (TTFields) with standard-of-care therapies met its primary end point in patients with metastatic non–small cell lung cancer (NSCLC).

A video-based teach-to-goal (TTG) intervention was able to improve inhaler technique over time among patients with chronic obstructive pulmonary disease (COPD) and asthma, according to a randomized controlled trial.

Patients who are members of racial minority groups are less likely to be prescribed insomnia medication.

Glofitamab is the first bispecific antibody with a fixed-duration treatment for adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL).

David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital, talks about the Timely Interventions for Diabetes Excellence dashboard, increases in continuous glucose monitoring, and more.