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Hypomethylating agents are a widely used treatment option in acute myeloid leukemia secondary to myeloproliferative neoplasms (MPNs), but careful monitoring of thromboembolic risk is needed for optimal outcomes.

Frist Cressey Ventures' main mission is to learn how it can partner with entrepreneurs to improve health care, said Chris Booker, partner with Frist Cressey Ventures.

Simplified treatments and patient-specific and systemic interventions can reduce nonadherence in patients.

Integrating primary care with behavioral health services, improving provider training on mental health, and policy changes were all noted as strategies to combat the rising mental health and substance abuse epidemic during a keynote session at AHIP 2022.

At a panel for the National Health Alliance, 3 experts talked about incorporating patient needs and requests in cancer care.

A population-based, observational, retrospective cohort study found that there was an association between migraines and ocular motor cranial nerve palsy.

A new genome-wide polygenic score was able to determine the risk of chronic kidney disease (CKD) in patients with a score in the top 2%.

A narrative review shows that diagnosing systemic lupus erythematosus (SLE) requires physicians to keep an open and inquisitive mind.

A recent study identified trends in blood counts, but did not find statistically significant associations between achieving hematological remission and clinical outcomes in polycythemia vera (PV) or essential thrombocythemia (ET).

Publishing their findings on the earliest treated infants to date, the researchers detailed the outcomes of 2 patients treated with nusinersen in their first week of life after receiving a spinal muscular atrophy (SMA) prenatal diagnosis.

Investigators note that the most recent systemic lupus erythematosus (SLE) classification system has quickly become the gold standard, but disease classification remains challenging.

Zahra Mahmoudjafari, PharmD, BCOP, clinical pharmacy manager at the University of Kansas Health System, explains some of the strategies that payers can use to improve cost management and increase patient access related to chimeric antigen receptor T-cell (CAR T) therapies.

While prevalence of restless leg syndrome (RLS) increases with age, some kids may have it while presenting symptoms of growing pains, explained John Winkelman, MD, PhD, medical director, sleep disorders clinical research program, Massachusetts General Hospital.

A university hospital saw an initial drop of new cases, but treatment efficacy was unaffected.

Using chronotropic response as a reference, study authors from Japan investigated the potential influence of exercise-induced heart rate on cardiac output reserve and exercise capacity among a cohort of patients with heart failure with preserved ejection fraction (HFpEF).

Elaine Siegfried, MD, professor of pediatrics and dermatology, Saint Louis University Health Sciences Center, addresses the comorbidity profile associated with atopic dermatitis and the utility of disease-modifying drugs to reduce risk of comorbid conditions.

A Mendelian randomization study found that there appears to be a causal relationship between inflammatory bowel disease (IBD) and psoriasis.

Real-world patients often differ from those eligible for clinical trials, and comparing results in both populations is a key step in fine-tuning treatment strategies for multiple myeloma.

Multisystem inflammatory syndrome (MIS) in children is a rare condition known to be associated with COVID-19, but more research is needed to identify at-risk patients and guide public health interventions.

Abstracts presented at the 2022 American Society of Clinical Oncology Annual Meeting show bevacizumab-awwb to be safe and effective for patients with metastatic colorectal cancer (mCRC) with high overall survival rates.

The patient was 52 years old and underwent a liver transplant 13 years after his hematopoietic stem cell transplant (HSCT) to treat his sickle cell disease (SCD).

Researchers found no evidence of increased risk for severe COVID-19 among children receiving biologic therapies for their psoriasis.

Emergency department (ED) visits and hospitalizations were 22% higher among cannabis users, with acute trauma and respiratory-related reasons as the primary causes for emergency care.

Whole-exome and RNA sequencing of early and late multiple myeloma tumor samples aimed to provide insight into disease drivers and phenotypes.

Researchers found that risk of adverse events and mortality did not increase following certain rheumatoid arthritis (RA) treatments.

Aetna announced it they would no longer be requiring prior approval for cataract surgeries starting in July.

Investigators from Toronto compared morbidity and mortality outcomes among patients with acute decompensated heart failure (ADHF) before and during the COVID-19 pandemic.