
Researchers found that fully vaccinated people with HIV have a 41% higher risk of COVID-19 breakthrough infection compared with people without HIV.

Researchers found that fully vaccinated people with HIV have a 41% higher risk of COVID-19 breakthrough infection compared with people without HIV.

On this episode of Managed Care Cast, we interview the lead author of a paper in the January issue of Health Affairs about what physicians know and don't know regarding their responsibilities to accommodate patients with disabilities when they come in for an office visit.

Investigators offered insight into disparities between countries regarding chronic kidney disease burden and suggestions on how those disparities can be addressed.

Children and adolescents with atopic dermatitis (AD) tended to have a higher number of delinquent behaviors than those without AD, including fighting, cheating on exams, and suspension.

For patients with multiple myeloma (MM) who are not eligible for transplant, should novel treatments be used right away? Or should clinicians save the best potential therapies for relapses, which are inevitable with this disease?

The Biden administration announced a requirement for insurance companies and group health plans to cover the cost of at-home COVID-19 tests; critical staffing shortages are reported nationwide amid record surges in COVID-19 cases and hospitalizations; the first-ever successful animal-to-human heart transplant was announced.

Across most questionnaire domains, patients reported improvements to their quality of life (QOL) while receiving treatment for spinal muscular atrophy (SMA) with nusinersen.

Following a review of trials that evaluated reduced sodium intake among patients with heart failure, investigators found no improvement to patient quality of life or their risks of mortality and hospital readmission.

Daridorexant belongs to a class of drugs known as a dual orexin receptor antagonists.

The study found 1 in 5 physicians felt acne had a negative impact on their working lives.

A recent analysis provides updated data on non–small cell lung cancer in the United States.

Posters from the Academy of Managed Care Pharmacy Nexus 2021 meeting detailed how coverage of genetic testing aligns with current guidelines as well as the potential budget impact of expanding access to comprehensive genomic profiling (CGP).


A combination of onabotulinumtoxinA and a calcitonin gene-related peptide monoclonal antibody appears effective and safe in patients with chronic migraine, according to real-world data.

Local immunoglobulin levels were found to be significantly higher in polyp tissue specimens, but not in the blood, of patients with nasal polyps.

New evidence suggests macrophage regulation could be an important area of inquiry in systemic lupus erythematosus, but the research is in its early stages.

Recent learnings about treating parenchymal brain metastases stem from several solid tumors, most commonly non-small cell lung cancer, breast cancer, and melanoma, all of which have benefitted from targeted treatments in recent years.

The 30-day readmission rate among patients receiving post-hospitalization at-home interventions was roughly half the rate of a control group.

A methodology to monitor patient-in-the-loop modes and faults was examined using a hybrid automata model that was able to replicate patient’s real-life operation modes.

President Joe Biden's vaccine mandate for large businesses was met with skepticism from the conservative-majority Supreme Court; COVID-19 hospitalization rates are rising for young children not yet eligible for vaccination; exercise is shown to lower risk of dementia even in those already presenting with symptoms.

Graft-versus-host disease (GVHD) is common, yet it is poorly understood and its symptoms can be difficult to recognize.

Risk of recurrent venous thromboembolism (VTE) in patients with chronic kidney disease (CKD) and VTE was significantly reduced in those who were treated with apixaban vs warfarin, investigators concluded.

Studies have shown that administering trilaciclib prior to chemotherapy can reduce myelosuppression and improve health-related quality of life. Jerome Goldschmidt, MD, said future studies will look at how it interacts with immunotherapy.

A large real-world analysis assessed age-related changes in commonly used visual field reliability indices and the potential mechanisms behind the trends.

Steven Pergam, MD, MPH, director of infection prevention at Seattle Cancer Care Alliance and infectious disease physician at Fred Hutchinson Cancer Research Center, describes the shifts in COVID-19 recommendations for patients with cancer and those receiving CAR T-cell therapy.

A significant link was found regarding incidence of diabetes and chronic rhinosinusitis (CRS) with nasal polyps, whereas CRS without nasal polyps was not associated with diabetes.

Gleaning data from real-world studies, investigators determined that commercially developed and open-source automated insulin dosing systems are safe and effective.

A novel treatment could offer an alternative to clindamycin (CL) in combination with rifampicin (RF), which comes with concerns of developing resistant bacteria due to long-term use.

Theresa Juday, RPh, director, Specialty Product Development, CVS Health, discusses the potential of cognitive behavioral therapy to address health disparities in underserved communities.

As noninvasive ventilation grows in popularity, new research examines when the therapy works, and when clinicians should be cautious.

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