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Mesenchymal stem cells are known to promote tumor growth and metastasis in multiple myeloma (MM), but a recent study found they may also inhibit the effects of the corticosteroid dexamethasone, a common medication for the hematologic malignancy.

Michael Ciarametaro, MBA, vice president of research at the National Pharmaceutical Council, highlights steps clinics can take to mitigate issues related to data collection regarding cell and gene therapies.

The CDC alerted doctors to look for symptoms of pediatric hepatitis following a cluster of unexplained cases of severe liver inflammation; President Joe Biden has released a national drug control strategy to prioritize harm reduction and treatment; kindergarten students fell behind on routine vaccinations during the COVID-19 pandemic.

Richard S. Isaacson, MD, outlines some of the recent developments in Alzheimer disease diagnoses and treatments.

To mark the nation's 52nd Earth Day, Robert Feder, MD, outlines how climate change will exacerbate mental health challenges and the importance of global efforts to address the crisis.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Patients with reduced DNA mismatch repair protein expression were more likely to respond to immune checkpoint inhibitors (ICIs), although this study had a small sample size.

Stephen Rozzo, PhD, associate vice president and head, Biologics Medical Affairs, Sun Pharma, North America, discussed findings of 2 phase 4 real-world studies on tildrakizumab, which showed that patients achieved significant improvement in severity and quality of life by week 4 of treatment.

Craig Pederson, Principal at Insight Health Partners, investigated how different health systems are creating physician alignment.

A combination of biology, access issues, and delayed diagnoses have contributed to disparities experienced by Black women with metastatic breast cancer, explained Hatem Soliman, MD, medical director of the Clinical Trials Office, Moffitt Cancer Center.

A new review article shows positive trends in survival, as scientists better understand the different types and symptoms of pulmonary arterial hypertension (PAH).

Interviewing both patients and providers, researchers found that while having effective treatments for hidradenitis suppurativa (HS) took precedence across the board, some priorities varied among the 2 groups.

An exhalation system with fluticasone was shown to significantly reduce nasal polyp score at 4 and 16 weeks compared with placebo, with improvements also observed in several patient-reported outcomes.

Increased uptake of biosimilars on par with the utilization rates of filgrastim biosimilars could have saved Medicare Part D $84 million in 2019.

Bill Vandivier, DO, outlines the challenges brought on by health care consolidation in his talk at the National Association of Managed Care Physicians Spring Managed Care Forum.

An observational, cross-sectional study found longer face mask wearing and nonstandard wearing of face masks were associated with dry eye in adults older than 20 years.

Patient education is an important step toward improving outcomes for racial and ethnic groups disproportionately affected by lupus, but a new report suggests payers and physicians also have more to learn about the problem.

Adherence to a Mediterranean diet, which modulates gut microbiota, offers some protection against Alzheimer disease, but results of the review indicated more research is needed to understand the effect on Parkinson disease.

The Department of Justice (DOJ) is seeking to appeal a federal judge’s ruling on the CDC’s travel mask mandate; the FDA issues a warning for harmful drug ingredients in dietary supplements; Florida's Department of Health releases its guidance on transgender care for young people.

The research, conducted in Germany, found that biologic treatment for asthma resulted in reduced health care resource utilization (HCRU), as seen in fewer hospitalizations and oral corticosteroid prescriptions as well as less sick leave.

Dexter Shurney, MD, MBA, MPH, chief health equity, diversity, and inclusion officer and chief medical officer at Adventist Health, explains the roles of health care systems and managed care organizations, and next steps to update policies, to ensure healthy food is available in all areas of the United States.

This investigation focused on use of additional services and incidence of new diagnoses among women who underwent a breast cancer screening MRI—having a low or average risk of the cancer—compared with a matched cohort who underwent mammography.

Researchers found point-of-care viral load (POC VL) tests have high sensitivity and specificity for detection of viral loads of at least 1000 copies/mL.

A recent study found that early use of a pulmonary rehabilitation program improved several measures of pulmonary function in patients with comorbid asthma, chronic obstructive pulmonary disease (COPD), and obesity.

According to a review, the availability of electronic cigarettes and vaping products to young people needs to be limited.

Elaine Siegfried, MD, professor of pediatrics and dermatology, Saint Louis University Health Sciences Center, discusses several pediatric patient populations with atopic dermatitis who are candidates for the use of systemic therapies.

Pediatric patients with psoriasis exhibited significant improvements in self-reported outcomes and objective measures of complete skin clearance when treated with ixekizumab vs placebo, with no new safety findings identified.

A study conducted in the Netherlands found older adults with depression were at greater risk of polypharmacy than those without depression.