The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
June 26th 2025
Primary and secondary end points were demonstrated in a phase 3 trial of subcutaneous marstacimab as treatment for patients with hemophilia A or B.
Health State Utility Scores for DMD-Related Impairment Need to Better Reflect Patient Input
January 12th 2024Patient-reported outcomes data regarding measures of health-related quality of life, also known as health state utilities, in Duchenne muscular dystrophy (DMD) are scarce, with current knowledge in this area concentrated in caregiver feedback.
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Hypofractionated Chemoradiation Regimen With an Adaptive SABR Boost Shows Promise in NSCLC
January 12th 2024An early-phase, dose-escalation study of a hypofractionated approach to concurrent chemoradiation using an an adaptive stereotactic ablative radiotherapy (SABR) boost showed promising results in patients with locally advanced, unresectable non–small cell lung cancer (NSCLC).
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Risk Evaluation and Mitigation Strategies [REMS] Program Considerations For Bispecific Therapy
January 12th 2024A panel discussion covers considerations within REMS programs aimed at minimizing risks associated with bispecific therapy. NOTE: Not all FDA-approved bispecific antibodies are associated with a REMS protocol.
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What Happens to Patients With Diabetes When Semaglutide Dosing Is Disrupted? Dr Ian Neeland Explains
January 11th 2024Possible long-term consequences for patients with diabetes forced to switch to alternative medications during the semaglutide shortage include the risk of losing ground in glycemic control, having uncontrolled diabetes with associated symptoms, and other adverse events.
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Zanubrutinib Shows Benefits Over Bendamustine Plus Rituximab Across CLL/SLL Subgroups
January 10th 2024Findings from the phase 3 SEQUOIA trial favored zanubrutinib over bendamustine plus rituximab in most biomarker-based subgroups of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) without deletion of the 17p chromosome.
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What We’re Reading: Doctor Payment Cuts; Menopause Drug; Student Mental Health Support
January 10th 2024Congress is being urged to reverse a cut to physicians’ Medicare payments; Bayer announced encouraging results on Monday of 2 phase 3 trials for its nonhormonal drug candidate meant to treat hot flashes; more students are turning to online mental health support rather than school counselors.
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Dr Ian Neeland Explains Why Semaglutide Shortage Impacts Injectable and Not Oral Version
January 10th 2024According to Ian Neeland, MD, there are 2 main reasons for the shortage of injectable semaglutide: the fact that oral semaglutide has not yet been tested for weight loss, and that most practitioners just overlook it as an option.
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What We’re Reading: Mask Mandates Return; Sugary Drink Sales Decline; WIC Program Problems
January 8th 2024COVID-19 subvariant JN.1 accounts for about 62% of US cases, resulting in mask mandates being reinstated in cities across the United States; sugary drink sales fell dramatically across 5 US cities after implementing taxes on them; it is difficult for Special Supplement Nutrition Program for Women and Children (WIC) participants to find approved items.
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Maternal T1D Associated With Risk of Congenital Heart Defects in Offspring
January 5th 2024A Finnish study found maternal type 1 diabetes (T1D) to be associated with a significantly higher risk of any congenital heart defect (CHD) in offspring, and that maternal overweight or obesity was associated with certain CHDs in offspring.
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