The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
May 17th 2024
Matching-adjusted indirect comparison methodology was utilized to compare ibrutinib arms across the ALPINE and ELEVATE-RR trials.
Phase 3 LyMa Trial: Rituximab After ASCT Increases OS in Mantle Cell Lymphoma
January 16th 2017Phase 3 results from the LyMa trial have shown that rituximab, after autologous stem cell transplant (ASCT), prolongs event-free survival, progression-free survival, and overall survival (OS) in previously untreated young patients with mantle cell lymphoma (MCL) following ASCT.
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Early Results Show Palbociclib Helps Sustain Patient Response to Ibrutinib in MCL
January 16th 2017Early phase 1 results show that including the cyclin-dependent kinase 4/6 inhibitor palbociclib in the treatment plan of patients with mantle cell lymphoma can help overcome resistance to ibrutinib.
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Patient and Provider Education on Pain in Cancer: A Cost-Saving Intervention
January 16th 2017An experiment by Park Nicollet Health Services to document personalized pain management goals for patients in oncology clinics lowered documented pain, while physician education on cost information helped reduce treatment costs.
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NCI Formulary a Big Support for Cancer Moonshot
January 11th 2017Described as a public—private partnership between the National Cancer Institute (NCI) and pharmaceutical and biotechnology companies, the NCI Formulary is expected to provide researchers rapid access to anticancer drugs for use in clinical trials.
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What We're Reading: HHS Will Take Swift Action on NC Medicaid Expansion Plan
January 10th 2017What we're reading: the Obama administration promises swift action on North Carolina's Medicaid expansion plan; FDA approves long-acting opioid; and a look at where President Barack Obama and President-elect Donald J. Trump stand on 5 areas of health policy and science.
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What We're Reading: Meals on Wheels Becomes the "Eyes and Ears" of Healthcare Systems
January 9th 2017What we're reading, January 9, 2017: how Meals on Wheels is becoming the "eyes and ears" of the healthcare system; unease brewing among Republicans about repealing Obamacare without a replacement; and a doctor at the Cleveland Clinic faces disciplinary actions after publishing anti-vaccine rhetoric.
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Delayed Chemotherapy Improves Survival in Surgically Resected Patients With NSCLC
January 9th 2017Delayed adjuvant chemotherapy, started up to 4 months following resection of non—small cell lung cancer (NSCLC) could still be beneficial to patients, according to a new study published in JAMA Oncology.
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First Patient Treated With Jakafi in Phase 2 Graft-Versus-Host Disease Study
January 3rd 2017The first patient has been treated with ruxolitinib (Jakafi), by Incyte Corporation, for steroid-refractory acute graft-versus-host disease, as part of the REACH-1 phase 2 trial. The trial is evaluating ruxolitinib in combination with corticosteroids.
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What We're Reading: Colorado's ACA Exchange Misused $9.7 Million
January 3rd 2017What we're reading, January 3, 2017: Colorado's Affordable Care Act exchange misused more than $9 million in federal funds; an over-the-counter birth control may be coming to the United States; and returning health data to patients could reduce health record breaches.
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The High Cost of Home Care for Children With Special Healthcare Needs
January 1st 2017Caring at home for children with special healthcare needs brings high costs to families. A study by researchers at the University of Southern California, Boston Children’s Hospital, and RAND Corp., placed the uncompensated medical cost at nearly $36 billion annually.
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Identifying the Inability to Heal Lungs in COPD
December 29th 2016Although chronic obstructive pulmonary disease (COPD) remains a leading cause of death around the world, the reason for why patients with COPD lose the ability to repair damage to their lungs is poorly defined. However, researchers at the Helmholtz Zentrium München may now have an idea of why this happens.
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Dr Grace C. Wright Explains How Vectra DA Helps Choose Treatments in RA
December 28th 2016Treating patients with rheumatoid arthritis can be difficult because the available drugs do not treat all symptoms. However, the Vectra DA test can help physicians more quickly understand if a patient is responding or needs to switch therapies, explained Grace C. Wright, MD, PhD, clinical associate professor of medicine and attending rheumatologist at New York University Langone Medical Center.
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Reducing Radiation Dose in Oropharynx Cancer Can Improve QOL
December 28th 2016A new clinical study to reduce the unwanted side effects of radiation in patients with human papillomavirus (HPV)—positive oropharynx cancers has found that reducing the dose of radiation can maintain the cure rates but avoid some of the late treatment-associated toxicities.
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What We're Reading: W.Va. Sues Drug Distributors for Fueling the Opioid Epidemic
December 28th 2016What we're reading, December 28, 2016: a county in West Virginia is suing 3 national drug distributors for allegedly fueling the opioid epidemic; CDC awards new funding as another Zika case is reported in Texas; and first drug to treat spinal muscular atrophy approved.
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Dr Sean Khozin Discusses How FDA Regulatory Process Helps Advance Precision Oncology
December 24th 2016FDA’s regulatory science activities are working to advance the field of precision oncology, in part by using predictive analyses to identify patients that may be good candidates for certain therapies, according to Sean Khozin, MD, MPH, senior medical officer at the FDA.
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