Opinion|Videos|December 9, 2025

Novel Pharmacotherapies and NCCN Guideline Recommendations

Explore the evolving landscape of desmoid tumor treatments, including chemotherapy, tyrosine kinase inhibitors, and emerging clinical trials.

Panelists discuss the questions below in this video.

  • Up until a few years ago, there were no-FDA approved therapies for desmoid tumors. What was the role of chemotherapy and other pharmacotherapies like tyrosine kinase inhibitors in these patients? What is their role in current practice?
  • What are the current NCCN guideline recommendations for treating desmoid tumors in patients?
  • How do you utilize these in your daily practice?
  • NCCN looks at surgery as a less preferred option vs. medication. How can this be incorporated into clinical practice, especially across specialties?

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