Opinion|Videos|October 7, 2025

The Potential of Prescription Drug Therapeutics (PDTs) in Schizophrenia

Panelists discuss how prescription digital therapeutics can serve the psychological and social components of schizophrenia treatment while potentially improving medication adherence, similar to how digital monitoring tools enhance outcomes in other chronic conditions like diabetes and hypertension.

Patients with schizophrenia may benefit significantly from prescription digital therapeutics (PDTs) as part of a comprehensive biopsychosocial treatment approach. While traditional biological treatments (medications) address neurotransmitter imbalances, PDTs can fulfill the psychological and social components of care. Many patients with schizophrenia are reluctant to spend extended time in traditional therapy sessions, but they may be more receptive to prescription digital therapy delivered through smartphones or other digital devices.

PDTs show promise for improving medication adherence among patients with schizophrenia, addressing the primary challenge in treatment. Similar to how patients with hypertension, diabetes, or asthma show better adherence when using daily monitoring devices, patients with schizophrenia may demonstrate improved medication compliance when engaging with daily digital therapeutics. Better adherence leads to reduced relapse rates, decreased homelessness and incarceration, and improved ability for patients to live independently, return to school, or maintain employment.

The potential benefits of PDTs extend beyond individual patients to their caregivers and families. Parents and family members of patients with schizophrenia often sacrifice their careers and life aspirations to provide care. By improving patient adherence to treatment and reducing caregiver burden, PDTs could help families maintain better quality of life while supporting their loved ones. This comprehensive approach to treatment recognizes that schizophrenia affects entire family systems, not just individual patients.

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