Pulmonary Arterial Hypertension

The AJMC® Pulmonary Arterial Hypertension compendium is a comprehensive resource for clinical news and expert insights for the progressive disorder, which is characterized by high blood pressure in the arteries that go from the heart to the lungs.

Latest News

Heartbeat EKG | Image Credit: © Tima-stock.adobe.com
Impedance Cardiography Offers Noninvasive Insight Into PAH Progression

May 15th 2025

Cardiac output and stroke volume as measured by impedance cardiography may hold potential to predict clinical deterioration from pulmonary arterial hypertension (PAH).

Walking analysis | Image Credit: © Microgen-stock.adobe.com
18MWT Contributes Valuable Feedback in Setting of PAH

May 6th 2025

Doctor holding generated image of lungs inside a heart | Image credit: Kiattisak - stock.adobe.com
PH, PAH Prevalence Higher in Medicaid, With Racial, Ethnic Disparities

April 28th 2025

Fitness device | Image Credit: © anatolir-stock.adobe.com
Wearable Tech Has Potential to Indicate PAH-Related Decline

April 21st 2025

Blood pressure graphic | Image Credit: © Dzianis Vasilyeu-stock.adobe.com
Worse CTD-PAH Prognosis Seen With Higher HFA-PEFF Score

April 8th 2025

More News

hypertension in pregnancy | Image Credit: peopleimages.com-stock.adobe.com
August 4th 2024

Hypertensive Disorders of Pregnancy on the Rise in Canada

Gayle Turim Dickstein
Researchers don’t fully understand why these disorders are increasing, but they declare that finding out should be a top priority.
representation of pulmonary hypertension | Image Credit: Angelov-stock.adobe.com
July 31st 2024

Early Treatment May Help Prevent PAH in High-Risk Patients

AJMC Contributor
New data from the single-center, open-label extension EDITA-ON study suggest that early treatment for pulmonary arterial hypertension (PAH) could benefit patients with systemic sclerosis and early pulmonary vascular disease.
doc reviewing lung report | Image Credit: meeboonstudio-stock.adobe.com
July 28th 2024

High Costs, Hospitalizations Linked to PH, ILD

Karen Jacobson-Sive
The hospitalization rate for patients with pulmonary hypertension (PH) and interstitial lung disease (ILD) doubled over a 2-year period, and total health care costs more than doubled over the same period.
pulmonary hypertension graphic | Image Credit: Dzmitry - stock.adobe.com
July 24th 2024

CTEPH Treatment, Management Varies Widely Across Globe

Jared Kaltwasser
A new report shows wide variability in terms of which patients with chronic thromboembolic pulmonary hypertension (CTEPH) are deemed eligible for pulmonary endarterectomy and balloon pulmonary angioplasty.
doc measuring BP in pregnany woman | Image Credit: Andrey Popov-stock.adobe.com.jpeg
July 17th 2024

Proteomics Promise: Not Yet Realized in Early Prediction of HDP

Gayle Turim Dickstein
Investigators hoped to use large-scale proteomics to help predict hypertensive disorders of pregnancy (HDP), using blood proteins obtained from individuals in their first trimester of pregnancy—but success has been elusive.
Doc taking BP | Image Credit: Prostock-studio-stock.adobe.com
July 10th 2024

Integrating Maternal BP Checks in Pediatric Visits Enhances Outcomes

Kimberly Rath, PharmD
A quality improvement program found that maternal blood pressure (BP) screening during early well-child visits significantly improves the early detection and management of postpartum hypertensive disorders.
Digital health care and network connection concept | Image Credit: © ipopba - stock.adobe.com
July 3rd 2024

Optimizing Pulmonary Hypertension Treatment With Digital Twin Models

Kimberly Rath, PharmD
Digital twin technology could personalize treatment for pulmonary hypertension, according to a recent study.
Pregnant monitoring BP | Image Credit: alfa27-stock.adobe.com
June 27th 2024

Hypertension Disorders of Pregnancy Largely Persist in the Postpartum Period

Karen Jacobson-Sive
More than 80% of pregnant patients with new-onset hypertensive disorder remain hypertensive after hospital discharge.
illustration of seizure | Image Credit: Teeradej-stock.adobe.com
June 25th 2024

Angiotensin Receptor Blockers Associated With Lower Epilepsy Risk in Hypertension

Karen Jacobson-Sive
Losartan may help stop the epileptic process in certain patients with hypertension.
Asian man with hypertension | Image Credit: jeffy1139-stock.adobe.com
June 18th 2024

Community Practitioner–Led Hypertension Program Yields Strong Results

Jared Kaltwasser
A Chinese study shows hypertension management led by nonphysicians can be safe and effective.
chlorthalidone | Image Credit: luchschenF-stock.adobe.com
June 12th 2024

Chlorthalidone May Be More Appropriate Diuretic for Patients With Hypertension, Previous CV Event

AJMC Contributor
Patients receiving chlorthalidone had lower rates of major cardiovascular (CV) events and noncancer-related deaths vs those receiving hydrochlorothiazide.
hypertension | Image Credit: relif-stock.adobe.com
June 4th 2024

Same Hypertension, Different Levels of Portal Engagement, Disparities Research Shows

Gayle Turim Dickstein
When patients are treated in primary care for high blood pressure, sociodemographic factors sway the rates at which they access patient portals, investigators found. This could influence their hypertension outcomes.
Blood pressure measurement | Image credit: interstid - stock.adobe.com
May 27th 2024

Early BP Reduction Shows No Benefit in Acute Stroke, but Outcomes May Vary by Stroke Type

Kimberly Rath, PharmD
A study found that prehospital blood pressure (BP) reduction had no impact on functional outcomes among patients with undifferentiated acute stroke, but that it may decrease the odds of poor outcomes following hemorrhagic stroke.
Doctor holding heart | Image credit: Pana Studio - stock.adobe.com
May 14th 2024

CVD Outcomes Linked to Youth Hypertension, Study Shows

Gayle Turim Dickstein
Closer monitoring of youth hypertension could lessen the disease in adults, reducing overall costs and morbidity related to cardiovascular disease (CVD), new research shows.
Ioana Preston, MD, a pulmonologist
May 3rd 2024

Addressing Unmet Needs and Disease Progression Challenges in Pulmonary Arterial Hypertension Management

Ioana Preston, MD
Ioana Preston, MD, discusses unmet needs in the management of pulmonary arterial hypertension (PAH) and the challenges associated with the progressive nature of the disease.
PA and nursing home resident | Image Credit: InsideCreativeHouse - stock.adobe.com
May 2nd 2024

Initiating BP Medication Linked to Higher Fall, Fracture Risks in Nursing Home Residents

AJMC Contributor
Among over 60,000 nursing home residents who initiated antihypertensive medication, rates of excess fractures due to falls per 100 person-years were as high as 5 among certain patient groups, such as those with dementia and high blood pressure (BP).
Ronald Oudiz, MD, FACP, FACC, FCCP, an expert on pulmonary arterial hypertension
May 1st 2024

New Therapeutic Frontiers in PAH

Ronald Oudiz, MD, FACP, FACC, FCCP
A cardiovascular specialist provides an overview of emerging therapies and targets in the PAH treatment space and how they address current unmet needs.
Ronald Oudiz, MD, FACP, FACC, FCCP, an expert on pulmonary arterial hypertension
May 1st 2024

Evolving Guidelines for PAH Treatment

Ronald Oudiz, MD, FACP, FACC, FCCP
Ronald Oudiz, MD, FACP, FACC, FCCP, discusses the latest guidelines and recommendations for the treatment of pulmonary arterial hypertension (PAH) and how they differ from previous versions.
Older obese man receives checkup | Image Credit: © Studio Romantic - stock.adobe.com
April 20th 2024

Reducing Time Sitting Can Help Lower BP in Older Adults, Randomized Trial Finds

AJMC Contributor
The randomized trial found that reducing sitting time over a 6-month period was association with reduced systolic blood pressure (BP) among a group of older patients with obesity and high rates of hypertension.
Biomarker DNA Strand Medical Research | Image Credit: iQoncept - stock.adobe.com
April 10th 2024

Targeting MACC1 Offers Promising Therapeutic Strategy for PAH

Luke Halpern
Positive responses seen following experiments involving metastasis-associated in colon cancer 1 (MACC1) indicate that the biomarker can be used to better diagnose and treat patients with pulmonary arterial hypertension (PAH).
Patient measuring blood pressure with a digital monitor | Image credit: vchalup-stock.adobe.com
April 3rd 2024

Pandemic Care Gaps Associated With Loss of Hypertension Control, Study Finds

Jared Kaltwasser
Surprisingly, the investigators found people with uncontrolled hypertension before the pandemic actually had a slightly higher chance of getting their blood pressure under control during the crisis.
FDA Approved
March 26th 2024

FDA Approves Sotatercept, First-in-Class Treatment for Adults With PAH

Julia Bonavitacola
Adults with pulmonary arterial hypertension (PAH) have a new treatment available with the FDA approval of sotatercept (Winrevair; Merck), an activin signaling inhibitor biologic.
FDA Approved Products or Drugs | Image credit: Olivier Le Moal - stock.adobe.com
March 25th 2024

FDA Approves Macitentan, Tadalafil Combination Tablet for Pulmonary Arterial Hypertension

Rose McNulty
The approval, which marks the first for a once-daily, single-tablet combination therapy for pulmonary arterial hypertension, is based on findings from the phase 3 A DUE study.
Doctor Measuring Blood Pressure Of Patient | Image Credit: Andrey Popov - stock.adobe.com
March 18th 2024

Study Assessing Blood Pressure Interventions in Rural Black Population Finds Little Effect

Jared Kaltwasser
Two strategies were tried, but neither outperformed usual care.
Patient suffers from hypertension | Image Credit: vchalup - stock.adobe.com
March 14th 2024

Nearly One-Third of US Adults Report Hypertension, Show CDC Data

AJMC Contributor
Prevalence of hypertension remained 30% throughout the study period and was lower than expected, based on a lower threshold for hypertension endorsed by guidelines in 2017.
Hypertension on a blackboard slate | Image Credit: relif - stock.adobe.com
March 7th 2024

SNAP Benefits May Help Improve Adherence to Antihypertensive Medications

AJMC Contributor
Among food-insecure patients on antihypertensive medication, receiving assistance through the Supplemental Nutrition Assistance Program (SNAP) was associated with improvements in medication adherence.
Health care costs - Valeri Luzina - stock.adobe.com
February 28th 2024

Coverage Expansion, Other Economic Policies May Yield Positive Impact on Hypertension Management

AJMC Contributor
Researchers of the review are underscoring the potential for economic policies to improve the management of hypertension for the millions of people throughout the United States with the condition who are at risk for cardiovascular disease.
Businessman holding and touching floating stethoscope 3D rendering - sdecoret - stock.adobe.com
February 21st 2024

Digital Health Interventions Can Reduce Hypertension Among Disadvantaged Populations

Luke Halpern
Numerous strategies were proposed, including an emphasis on community-based interventions that can reduce psychological stressors associated with clinical settings.
Combination Therapies Provide Optimal Hypertensive Control in Patients Taking Ibrutinib
February 17th 2024

Combination Therapies Provide Optimal Hypertensive Control in Patients Taking Ibrutinib

Jared Kaltwasser
The retrospective study found patients on Bruton’s tyrosine kinase inhibitors are similar to the general population in the sense that it usually takes at least 2 anti-hypertensive drugs to control blood pressure.
Salt and heart disease | Image credit: Sharif - stock.adobe.com
February 12th 2024

Salt Substitute Reduces Incidence of Hypertension in Older Adults

Luke Halpern
For the first time, investigators found that the replacement of salt with a salt substitute not only reduced hypertension, but did not also increase hypotension, a key factor for older adults.
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