Type 1 Diabetes

The AJMC® Type 1 Diabetes compendium is a comprehensive resource for news and interviews about this chronic autoimmune condition.

Latest News

AJMC
Cost-Effectiveness of the MiniMed 780G System for Type 1 Diabetes

April 10th 2025

A new technology for management of diabetes is cost-effective for patients in the US with type 1 diabetes compared with traditional treatments.

counting calories | Image Credit: Andrii Symonenko-stock.adobe.com
T1D Management: Carbohydrate Counting With Technology

June 27th 2024

older person with T1D | Image Credit: dorde-stock.adobe.com
More People With T1D Are Living Into Old Age

June 19th 2024

blood sugar control concept | Image Credit: Phruetthiphong-stock.adobe.com
AYA With T1D Have Suboptimal Glucose Control

June 16th 2024

T1D icon | Image Credit: MQ-Illustrations-stock.adobe.com
Gender May Affect Whether, Why Patients With T1D Exercise

June 12th 2024

More News

Continuous glucose monitor | Image credit: Pixel-Shot - stock.adobe.com
January 16th 2024

Real-Time CGM Shows Benefits Over Intermittently Scanned CGM in T1D

Rose McNulty
In a systematic review and meta-analysis, real-time continuous glucose monitoring (CGM) demonstrated benefits in terms of time in range, hypoglycemia, and hyperglycemia among patients with type 1 diabetes (T1D).
Glucose monitor | Image credit: Andrey Popov - stock.adobe.com
January 12th 2024

Real-Time CGM With Predictive Alarm Improves Glycemic Control in T1D

Rose McNulty
A study of adolescents with type 1 diabetes (T1D) found that real-time continuous glucose monitoring (CGM) with a predictive hypoglycemia alarm reduced the time spent below range.
Maternal diabetes | Image credit: Dragana Gordic - stock.adobe.com
January 5th 2024

Maternal T1D Associated With Risk of Congenital Heart Defects in Offspring

Rose McNulty
A Finnish study found maternal type 1 diabetes (T1D) to be associated with a significantly higher risk of any congenital heart defect (CHD) in offspring, and that maternal overweight or obesity was associated with certain CHDs in offspring.
Kevan Herold, MD
December 27th 2023

Research Shows Efficacy of Teplizumab in Newly Diagnosed T1D: Dr Kevan Herold

Rose McNulty
In recently published data from the phase 3 PROTECT trial, teplizumab slowed the progression of type 1 diabetes in children and adolescents.
Analysis Shows Association Between Hypothyroidism and T1D
December 25th 2023

Analysis Shows Association Between Hypothyroidism and T1D

Connor Iapoce
Mendelian randomization analyses demonstrated a causal relationship between hypothyroidism and diabetes, along with its related microvascular complications.
Top 5 Type 1 Diabetes Articles of 2023
December 24th 2023

Top 5 Most-Read Type 1 Diabetes Articles of 2023

Rose McNulty
Our top-read type 1 diabetes articles of 2023 covered increases in rates of pediatric diabetes early in the COVID-19 pandemic, novel therapies for T1D, and links between patient characteristics and T1D outcomes.
Dr Kevan Herold
December 15th 2023

Dr Kevan Herold Explains Teplizumab's Potential in Newly Diagnosed T1D

Rose McNulty
Kevan Herold, MD, professor of immunobiology and medicine at Yale School of Medicine, discussed recently published results from the PROTECT trial of teplizumab in patients newly diagnosed with type 1 diabetes (T1D).
Type 1 diabetes - Vitalii Vodolazskyi - stock.adobe.com
December 11th 2023

Study Finds Baricitinib Could Delay Progression of Type 1 Diabetes

Patrick Campbell
A trial comparing baricitinib against placebo in people with new-onset type 1 diabetes suggests use could contribute to the preservation of β-cell function.
Global health | Image credit: bahtiarmaulana – stock.adobe.com
December 1st 2023

Review Highlights Variation in Pediatric T1D Incidence by Country, Age

Hayden E. Klein
The highest incidence of pediatric type 1 diabetes (T1D) over the past 22 years was seen in Finland, high-income North American regions, and children aged 5 to 14 years.
Type 1 Diabetes | Image credit: Svetlana - stock.adobe.com
November 22nd 2023

Study Shows Higher Infection Risk in Patients With T1D in Primary, Secondary Care

Rose McNulty
Researchers concluded there is a clinically important increase in infection risk among patients with T1D in both primary care and hospital settings, and that guidelines must be developed to reflect this risk and encourage earlier treatment.
Walking | Image credit: kieferpix - stock.adobe.com
November 18th 2023

Physical Activity Level Could Influence Polyneuropathy Risk in Type 1 Diabetes

Patrick Campbell
A study from investigators in Italy sheds further light on the relationship between physical activity and diabetic polyneuropathy risk in patients with type 1 diabetes.
Diabetes | Image credit: Vitalii Vodolazskyi - stock.adobe.com
November 15th 2023

Recent T1D Research Contradicts Common Assumptions About Patients

Rose McNulty
Michael Fang, PhD, researcher and assistant professor in the division of Cardiovascular and Clinical Epidemiology at Johns Hopkins University, discussed recent findings in the type 1 diabetes (T1D) space that may alter the way providers address diabetes diagnoses.
High BMI Associated With Increased Risk of Type 1 Diabetes
November 10th 2023

High BMI Associated With Increased Risk of Type 1 Diabetes

Joshua Fitch
In a systematic and meta-analysis review of cohort studies that featured nearly 1.7 million individuals, study authors concluded that there is an association between high body mass index (BMI) and an increased risk of incident type 1 diabetes.
Illustration of neurons | Image credit: Igor - stock.adobe.com
November 2nd 2023

Glucose Fluctuation Linked to Slowed Nerve Conduction Velocity in Youth With T1D

Rose McNulty
High glucose variability in children and young adults with type 1 diabetes (T1D) strongly predicted slowed nerve conduction velocity, a forerunner of diabetic peripheral neuropathy, in a recent study.
Type 1 diabetes | Image credit: Vitalii Vodolazskyi - stock.adobe.com
October 26th 2023

Hybrid Closed-Loop Therapy Effective for Pregnant Women With Type 1 Diabetes

Connor Iapoce
Results from the AiDAPT trial show hybrid closed-loop therapy significantly improves maternal glycemic control during pregnancy complicated by T1D.
girl with diabetes | Image credit: Africa Studio - stock.adobe.com
October 21st 2023

Phase 3 Data Show Teplizumab Slows T1D Progression in Children, Adolescents

Skylar Jeremias
Phase 3 data presented at ISPAD found that teplizumab-mzwv (Tzield) was better at slowing the progression of type 1 diabetes (T1D) in newly diagnosed children and adolescents.
|Cheerful Active Senior Couple | Image credit: valeriia - stock.adobe.com
October 14th 2023

Unstructured Physical Activity Lowers Glucose, but Increases Risk of Hypoglycemia in T1D

Giuliana Grossi
Results show engaging in unstructured physical activities, even those of low intensity and carried out in the morning and early afternoon, is linked to reduced average glucose levels throughout the day and night.
Type 1 diabetes - Vitalii Vodolazskyi - stock.adobe.com
October 7th 2023

Many Cases of Adult-Onset T1D Are Diagnosed After Age 30, Study Finds

Rose McNulty
In the overall population of more than 1.3 million US adults, 37% of patients reported being diagnosed with T1D after 30 years, with men and racial or ethnic minorities diagnosed later compared with women and non-Hispanic White adults.
Testing blood sugar - erika8213 - stock.adobe.com
October 6th 2023

Patients With T1D Achieve Insulin Independence With Islet Cell Therapy

Victoria Johnson
Updated findings from a phase 1/2 trial of stem-cell derived islet cell therapy for type 1 diabetes (T1D) showed improved glycemic control and a reduction in insulin dependence.
Continuous glucose monitoring | Image credit: Pixel-Shot - stock.adobe.com
September 25th 2023

Patients With T1D Report Improved Management Using DIY-CGM vs isCGM

Rose McNulty
The study aimed to determine the perceived advantages and disadvantages of the smartwatch-integrated, do-it-yourself continuous glucose monitoring (DIY-CGM) device from the perspective of patients with type 1 diabetes (T1D).
Type 1 diabetes | Image credit: Vitalii Vodolazskyi - stock.adobe.com
September 23rd 2023

Endotrophin Levels Could Signal Elevated Kidney Risk in Type 1 Diabetes

Patrick Campbell
Elevated serum endotrophin levels, but not urinary endotrophin levels, predict increased risk of kidney complications and mortality in type 1 diabetes.
Testing glucose | Image credit: AntonioDiaz - stock.adobe.com
September 22nd 2023

Sociodemographic, Clinical Variables Impact Metabolic Control in Adolescents With T1D

Rose McNulty
Self-care adherence, family support and functioning, and school support also indirectly affected the relationship between sociodemographic and clinical variables and metabolic control, a study found.
Woman sleeping next to alarm clock | Image credit: stokkete - stock.adobe.com
September 15th 2023

Sleep Timing Variability Linked to Less Time in Target Glucose Range in T1D

Rose McNulty
The findings suggest that reducing sleep timing variability may help improve metabolic control, but the relationship between glucose levels and sleep variability requires further research.
Business candle stick graph chart of stock market investment trading on blue background. Bullish point, Trend of graph. Eps10 Vector illustration. | Image Credit: ABC Vector – stock.adobe.com
June 30th 2023

Pediatric Diabetes, DKA Rates Increased During Early COVID-19 Pandemic

Hayden E. Klein
Type 1 diabetes incidence was 1.14 times higher in the first year and 1.27 times higher in the second year of the COVID-19 pandemic, compared with the 12 months before the pandemic.
stack of books with reading glasses on top
June 28th 2023

ADA Standards of Care Updates Cover Teplizumab for Delaying T1D, Emphasis on NAFLD Management

Hayden E. Klein
The American Diabetes Association (ADA) announced updates to multiple sections of its Standards of Care in Diabetes–2023, as announced at the ADA 83rd Scientific Sessions.
Paper with words diabetes type 1 and glasses. | Image Credit: Vitalii Vodolazskyi – stock.adobe.com
June 23rd 2023

VX-880 Shows Promise for Insulin, Glucose Management in T1D in New Data

Hayden E. Klein
New findings show that VX-880, a stem cell-derived islet cell therapy, can restore endogenous insulin secretion and improve glycemic control in people living with type 1 diabetes (T1D).
David Maahs, MD, PhD
June 20th 2023

Dr David Maahs Highlights Unmet Needs in Youth T1D Care

Hayden E. Klein
Improving access to diabetes technology so that everyone can benefit is a top priority, said David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital.
David Maahs
June 16th 2023

Applying 4T Study Findings to the Managed Care Space: Dr David Maahs

Hayden E. Klein
David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital, talks about the Timely Interventions for Diabetes Excellence dashboard, increases in continuous glucose monitoring, and more.
David Maahs, MD, PhD
June 8th 2023

Early CGM Initiation, Remote Data Review Decreased HbA1C in Youth With T1D: Dr David Maahs

Hayden E. Klein
The pilot 4T study showed consistent hemoglobin A1C improvement in all children with type 1 diabetes (T1D) after 1 year, underscoring the importance of early continuous glucose monitoring (CGM) following diagnosis, explained David Maahs, MD, PhD, professor of pediatrics at Stanford University and division chief of pediatric endocrinology at Lucile Packard Children’s Hospital.
person standing on scale
June 7th 2023

Being Underweight May Increase All-Cause Mortality Risk in T1D

Hayden E. Klein
In a review of adults with type 1 diabetes (T1D), having a body mass index (BMI) <18.5 kg/m2 increased the risk of all-cause mortality by 3.4 times compared with normal BMI.
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