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Positive topline data from the phase 3 BRUIN CLL-313 showed pirtobrutinib's efficacy in the frontline setting.

This case highlights the diagnostic complexity and clinical management challenges of dual hematologic malignancies.

Findings from the ROCKET-SHUTTLE trial reveal the benefits of combining the anti-OX40 monoclonal antibody with topical therapies for atopic dermatitis.

The approval allows all patients 12 years and older to use pembrolizumab and berahyaluronidase alfa-pmph for subcutaneous injection for solid tumor indications approved for intravenous pembrolizumab.

Research shows more than a third of patients with rheumatoid arthritis met criteria for frailty, with prefrailty and robust groups closely following.

Patients with acute exacerbations of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis face steep odds and benefit from palliative care.

A randomized trial shows low-dose aspirin halved recurrence rates in patients with PI3K pathway gene alterations.

Research reveals that patients with both rheumatoid arthritis and MASH cirrhosis face significantly higher cardiovascular risks.

The Oncotype DX 21-gene recurrence score helps guide adjuvant therapy in women with early-stage breast cancer and low genomic risk.

Tirzepatide’s cost-effectiveness provides key evidence for policy makers implementing clinical coverage decisions.

With vaccination rates slipping and new policies emerging, parents need to know what’s changing as kids head back to the classroom.

Efgartigimod shows promising early response in generalized myasthenia gravis, especially in patients with short disease duration and severe bulbar symptoms.

Iron dysregulation significantly impacts multiple sclerosis progression, linking iron levels to neuroinflammation, demyelination, and potential therapeutic strategies.

Although rarely used in psoriatic arthritis (PsA), combination targeted therapy (CTT) appears to have a safety profile comparable to standard therapy.

Despite higher burden of metabolic issues, individuals with HIV were not more metabolically ill.

Accessibility to gender-affirming surgery needs to be improved for transgender, nonbinary, and gender-diverse individuals.

Ruxolitinib cream 15 mg/g provided rapid, meaningful repigmentation and improved quality of life for adults with nonsegmental vitiligo.

A Japanese study links external eating patterns to weight loss and glycemic improvements with glucagon-like peptide-1 receptor agonists.

Refat Rasul Srejon, MPH, says reducing opioid-related emergency department (ED) visits among young adults requires strategies like medication-assisted treatment and targeted outreach.

Increased use of neoadjuvant chemotherapy (NACT) with interval debulking surgery has changed surgical practice patterns, improving complete resection rates and reducing postoperative complications.

The governors California, Oregon, Washington, and Hawaii came together to announce their winter virus recommendations.

The adoption of technologies like telehealth and health information exchange increased over time, but hospitals in the most disadvantaged areas were behind.

Net health care costs would also increase by billions of dollars should pre-exposure prophylaxis become less accessible.

Bariatric surgery is more efficient at increasing weight loss and more cost-effective than GLP-1 RAs.

Elena Losina, PhD, codirector of the Orthopedics and Arthritis Center for Outcomes Research at Brigham and Women’s Hospital, discusses the cost-effectiveness of varying weight loss interventions.

Susan Monarez, PhD, warns of absent evidence, political pressure, and risks to public health after being fired last month by HHS Secretary Robert F. Kennedy Jr.

New demands to follow the most favored nation executive order could lead to some compliance but it is unknown just how effective they will be across all health care.

Although children living with myopia taking atropine did experience an increased incidence of cataracts, glaucoma, or maculopathy, it is unclear if this risk was confounded by myopia severity.