The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
May 17th 2025
Novel therapies for multiple myeloma (MM), including chimeric antigen receptor T-cell and bispecific antibodies, extend lives but raise concerns about treatment costs and adherence, and they haven't replaced stem cell transplantation, Harsh Parmar, MD, of Hackensack University Medical Center, explains.
Making the Case for Integrated Care and Physician Engagement With Addiction Patients
October 30th 2017A back to back session and panel at the falls’ ACO & Emerging Healthcare Delivery Coalition focused on the importance of utilizing integrated healthcare to treat individuals with addiction and ensuring physicians are educated on understanding addiction.
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Prochlorperzine Is More Effective for Treating Migraines in the ED Than Commonly Used Drugs
October 29th 2017Hydromorphone is commonly used in hospital emergency rooms to treat patients with migraines; however, the drug is less effective than the drug prochlorperazine used with diphenhydramine, according to research.
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Study Finds Significant Response of Nivolumab-Refractory Lung Cancer to Salvage Chemotherapy
October 28th 2017Physicians should be cautious when treating patients with lung cancer after progression on nivolumab because nivolumab-refractory lung cancer could have a significant response to salvage chemotherapy, according to a new study.
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Increased Mortality Rates Found in Patients With Borderline Pulmonary Hypertension
October 26th 2017A new study found that patients with borderline pulmonary hypertension (mPAP values of 19 to 24 mm Hg) should be considered an at-risk subgroup with increased mortality compared with patients with lower mean pulmonary arterial pressures.
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The Argument for Caution When Judging Industry Payments to Dermatology Clinical Guideline Authors
October 26th 2017After a study reported that physicians who authored dermatology clinical guidelines didn't always fully disclose financial conflicts of interest, the American Academy of Dermatology urged the public to view the findings with caution.
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Stakeholders Weigh-in on Payment Reform in Cancer Care
October 25th 2017Tuple Health, a healthcare technology startup, interviewed some of the stakeholders participating in value-based care delivery and OCM, to gain their perspective of the state of cancer care and healthcare reform. The results were presented at the Community Oncology Alliance Payer Exchange Summit on Oncology Payment Reform.
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Evidence-Based Guidelines to Reduce Excessive Laboratory Testing
October 25th 2017In addition to the cost, the excessive overuse of laboratory testing causes patient discomfort and can lead to hospital-acquired anemia, which results in additional testing, prolonged hospitalizations, unnecessary transfusions, and increased mortality for patients with cardiopulmonary diseases.
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This Week in Managed Care: October 20, 2017
October 20th 2017This week, the top managed care news included the bipartisan deal to stabilize the Affordable Care Act's insurance markets; coverage from the Academy of Managed Care Pharmacy 2017 Nexus; and a plan to reduce clinician burnout at the computer.
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Tocilizumab Associated With Higher Risk of Neutropenia Among Biologic DMARDs
October 20th 2017History of neutropenia with methotrexate, concurrent treatment with synthetic disease-modifying antirheumatic drugs (sDMARDs), and tocilizumab were risk factors for developing neutropenia while on biologic DMARDs (bDMARDs), according to a study published in The Journal of Rheumatology.
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Kite Pharma's CAR T-Cell Treatment Approved, Cheaper Than Tisagenlecleucel
October 19th 2017Axicabtagene ciloleucel (Yescarta) has been approved to treat adult patients with diffuse large B-cell lymphoma who have not responded to or who have relapsed after at least 2 other kinds of treatment.
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Dr Deepak Bhatt on the Impact of the COMPASS Trial on Standard of Care
October 19th 2017The COMPASS trial results could reshape the standard of care for patients with coronary artery disease (CAD) and peripheral artery disease (PAD), according to Deepak Bhatt, MD, MPH, of Brigham and Women's Hospital and Harvard Medical School.
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The Case for Eliminating the Neutropenic Diet
October 18th 2017Although there is no scientific evidence that a specific diet reduces risk of infection in patients experiencing neutropenia, it is a common strategy in cancer care. Research presented at the 42nd Annual Congress of the Oncology Nursing Society determined that the popular neutropenic diet can be eliminated from practice.
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PD-1 Inhibitor Doubled Survival in Treatment-Naive Patients With mNSCLC
October 18th 2017The 2-year follow up results from the Keynote-024 trial were presented at the 18th World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer in Yokohama, Japan.
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COPD Medication Regimens Linked To Disease Severity and Comorbidities
October 18th 2017Patients with chronic obstructive pulmonary disease (COPD) often require complex medication regimens that are associated with significant disease severity, comorbidities, and multidimensional indices, according to a study.
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Formulary Considerations: The Past, Present, and Future
October 16th 2017The hospital formulary system is an ongoing process that evaluates and selects the safest, most effective, and most economical care for hospitalized patients. As healthcare continues to change, so will the formulary management process.
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AJMC®tv Interviews, October 2017
October 13th 2017AJMC®TV interviews let you catch up on what’s new and important about changes in healthcare, with insights from key decision makers-from the clinician, to the health plan leader, to the regulator. When every minute in your day matters, AJMC®TV interviews keep you informed. Access the video clips at ajmc.com/interviews.
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Stand Up To Cancer Awards $5.5 Million for Epigenetic Immunotherapy Trials
October 13th 2017While many lung and bladder cancer patients respond well to immunotherapy, they eventually succumb to the disease because the immune system can not detect the cancer cells. Two clinical trials will combine immunotherapy with epigenetic agents in order to allow the immune system to recognize and destroy the cancer cells.
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