Chronic Kidney Disease

The AJMC® Chronic Kidney Disease compendium is a comprehensive resource for clinical news and expert insights on the condition and treatment of loss of kidney function.

Latest News

The researchers noted diabetes and hypertension are both modifiable with appropriate management that brings patients to guidelines-based targets. | Image Credit: Crystal light - stock.adobe.com
PCPs Have Unique Opportunity to Detect, Manage CKD

August 14th 2025

As the prevalence of chronic kidney disease (CKD) continues to rise, empowering primary care providers (PCPs) with the tools, training, and collaborative frameworks needed for optimal management is a public health priority, emphasize the researchers.

In a primary care setting, the model could be used to identify potential cases of CKD, allowing for early referral to specialty clinics. | Image credit: filins - stock.adobe.com
Retinal Images Fuel Noninvasive CKD Detection Model

August 12th 2025

stomach ache and kidney disease | Image credit: dream@do - stock.adobe.com
New Data Unveil the Hidden Link Between CKD and GERD

July 31st 2025

nurse discussing chronic kidney disease | Image credit: NanSan - stock.adobe.com
Nurses Emerge as Potential Leaders in Implementing CKD Care Strategies

July 29th 2025

Image Credit: Dusan Petkovic - stock.adobe.com
Drinking Water Contaminants Linked to Higher Chronic Kidney Disease Risk

July 11th 2025

More News

CMS Seeks Incentives for At-Home Dialysis in Wake of COVID-19
July 7th 2020

CMS Seeks Incentives for At-Home Dialysis in Wake of COVID-19

Mary Caffrey
End-stage renal disease has long been one of the most expensive and debilitating conditions that affects Medicare beneficiaries. Not only does dialysis cost $90,000 a year—those awaiting a kidney transplant automatically qualify for Medicare—but the need to travel to a dialysis center multiple times a week disrupts employment and home life.
Frequently Prescribed Allopurinol No Better Than Placebo for CKD in Head-to-Head Trial
July 4th 2020

Frequently Prescribed Allopurinol No Better Than Placebo for CKD in Head-to-Head Trial

Mary Caffrey
Results from the University of New South Wales appeared in the New England Journal of Medicine. The co-lead investigator said the results show the need for more treatment options in chronic kidney disease.
Study of Fat Cells May Hint at Target in Chronic Renal Failure
July 1st 2020

Study of Fat Cells May Hint at Target in Chronic Renal Failure

AJMC Staff
Previously, fat cells, called adipocytes, were not known to have a role in renal failure-associated cardiomyopathy.
Dana-Farber Scientists Find Biomarker for Kidney Cancer
June 25th 2020

Dana-Farber Scientists Find Biomarker for Kidney Cancer

Mary Caffrey
A coauthor of the study said that if the noninvasive test was used more widely, before kidney cancers have spread, fewer people would die from the disease.
Kidney Failure Due to Acute Injury Deadlier Than Diabetes, Data Show
June 23rd 2020

Kidney Failure Due to Acute Injury Deadlier Than Diabetes, Data Show

Mary Caffrey
Acute kidney injury is a sudden onset of kidney damage that causes waste products to build up in the body. These episodes have become more common during the coronavirus disease 2019 pandemic, causing kidney failure in some previously healthy patients who had no prior history of renal problems.
Differences in Basal Insulins for Patients in Renal Failure
June 20th 2020

Differences in Basal Insulins for Patients in Renal Failure

Mary Caffrey
In a poster titled “Basal Insulins in Advanced Renal Failure: Time for a Paradigm Shift,” authors compared the safety and efficacy of insulin degludec (Tresiba) with insulin glargine 100U (Lantus) among patients with stage 3 and stage 4 chronic kidney disease (CKD).
Lexicon's Sotagliflozin Meets Mark in T2D With Moderate Renal Impairment, but Misses on Sicker Patients
June 19th 2020

Lexicon's Sotagliflozin Meets Mark in T2D With Moderate Renal Impairment, but Misses on Sicker Patients

Mary Caffrey
Two studies evaluated how well the dual inhibitor reduced glycated hemoglobin (A1C) while measuring instances of hypoglycemia and other safety measures.
Research Into Key Protein Could Lead to Target to Halt CKD
June 13th 2020

Research Into Key Protein Could Lead to Target to Halt CKD

Mary Caffrey
Experiments with the protein Cx43 show that it could be a "druggable target" to prevent renal decline.
Cardiorenal Effects of Newer Diabetes Therapies to Be Explored at ADA
June 12th 2020

Cardiorenal Effects of Newer Diabetes Therapies to Be Explored at ADA

Mary Caffrey
Recently, cardiorenal outcomes have gained attention, as SGLT2 inhibitors in particular have been shown to prevent renal decline and reduce the risk of patients with type 2 diabetes (T2D) progressing to kidney failure
National Kidney Foundation Issues Statement on Health Disparities, Racial Violence
June 6th 2020

National Kidney Foundation Issues Statement on Health Disparities, Racial Violence

AJMC Staff
The NKF, which works to address health issues for 37 million people in the United States with kidney disease, said Floyd’s death and the ongoing coronavirus disease (COVID-19) pandemic both highlight disparities in health outcomes between minority groups and whites.
Most Americans Unaware of COVID-19's Effects on the Kidneys
June 6th 2020

Most Americans Unaware of COVID-19's Effects on the Kidneys

Mary Caffrey
Patients who have no history of kidney damage are ending up with acute kidney injury, which could leave them at higher risk of chronic kidney disease and dialysis.
Medicare Advantage Gets 2021 Pay Bump Amid COVID-19 Rule Changes
April 7th 2020

Medicare Advantage Gets 2021 Pay Bump Amid COVID-19 Rule Changes

Mary Caffrey
The rate increase comes as the agency is easing up on quality reporting requirements to give health sytems breathing room amid the pandemic. Monday’s announcement also clarified some payment changes for end-stage renal disease.
This Week in Managed Care: April 3, 2020
April 4th 2020

This Week in Managed Care: April 3, 2020

This week, the top managed care news includes a CDC report says diabetes is the condition most linked with coronavirus disease 2019, CMS temporarily suspends rules to give hospitals more capacity during the COVID-19 pandemic, and a late-stage trial for dapagliflozin ends early after showing efficacy for chronic kidney disease.
CMS Temporarily Suspends Many Regulations to Give Hospitals More Capacity During Pandemic
March 31st 2020

CMS Temporarily Suspends Many Regulations to Give Hospitals More Capacity During Pandemic

Allison Inserro
The changes are aimed at helping hospitals increase their capacities for the sickest patients; expand the pool of local healthcare providers who are available to work; eliminating ordinary paperwork and documentation requirements; expanding Medicare coverage for respiratory-related devices and equipment for any medical reason; and expanding telehealth in Medicare by covering more than 80 additional services.
CDC, ASN Address COVID-19 Challenges in Dialysis Setting
March 30th 2020

CDC, ASN Address COVID-19 Challenges in Dialysis Setting

Gianna Melillo
In a response to the coronavirus disease 2019 (COVID-19) pandemic, the American Society of Nephrology (ASN) has hosted series of webinars outlining CDC recommendations and policy changes for challenges in the dialysis setting.
Dr Cynthia Delgado: Research Needed on Disability Experiences of Patients With CKD Over Time
February 28th 2020

Dr Cynthia Delgado: Research Needed on Disability Experiences of Patients With CKD Over Time

Although many investigators have pushed the envelope in researching how patients with chronic kidney disease (CKD) experience disabilities, there is still a need for more knowledge on how those disabilities evolve over time, according to Cynthia Delgado, MD, associate professor of medicine at the San Francisco Veterans Affairs Medical Center and University of California San Francisco Medical Center.
Dr Cynthia Delgado Outlines How Frailty Affects Outcomes in Patients Receiving Hemodialysis
February 20th 2020

Dr Cynthia Delgado Outlines How Frailty Affects Outcomes in Patients Receiving Hemodialysis

Frailty significantly raises the risk of developing disabilities as a result of hemodialysis, so even patients who are intermediately frail should be monitored, said Cynthia Delgado, MD, associate professor of medicine at the San Francisco Veterans Affairs Medical Center and University of California San Francisco Medical Center.
Dr Joseph Vassalotti Describes Ways to Empower Primary Care Clinicians to Treat Kidney Disease
February 13th 2020

Dr Joseph Vassalotti Describes Ways to Empower Primary Care Clinicians to Treat Kidney Disease

Educating primary care clinicians on how to manage chronic kidney disease in the primary care setting can help avoid referrals for nephrology consults that aren’t needed, said Joseph Vassalotti, MD, clinical professor at Icahn School of Medicine at Mount Sinai and chief medical officer of the National Kidney Foundation.
PAPER OF THE WEEK: When Patients With Kidney Failure Still Don't Take Medication
February 8th 2020

PAPER OF THE WEEK: When Patients With Kidney Failure Still Don't Take Medication

Mary Caffrey
The article identifies issues such as poor socioeconomic background and lack of family and social support as factors in poor medication adherence, which today are recognized as social determinants of health
Medicare Advantage Proposal Includes Steps to Implement Kidney Care Plan
February 7th 2020

Medicare Advantage Proposal Includes Steps to Implement Kidney Care Plan

Mary Caffrey
The plan represents the latest element of the Trump administration’s comprehensive approach to renal care, which seeks to keep patients from advancing to dialysis. For those who do, the plan promotes transplants and home dialysis options.
Dr Joseph Vassalotti Explains How CKDintercept's Components Can Improve Kidney Care
February 5th 2020

Dr Joseph Vassalotti Explains How CKDintercept's Components Can Improve Kidney Care

CKDintercept, the primary care initiative of the National Kidney Foundation, involves multiple strategies aimed at improving the quality of kidney care, explained Joseph Vassalotti, MD, clinical professor at Icahn School of Medicine at Mount Sinai and chief medical officer of the National Kidney Foundation.
Dr Cynthia Delgado Explains How Patients With Disabilities Experience Kidney Care Differently
February 2nd 2020

Dr Cynthia Delgado Explains How Patients With Disabilities Experience Kidney Care Differently

Physical disabilities may make it difficult for patients with chronic kidney disease to follow provider recommendations and achieve a good therapeutic alliance, which can lead to increased burden of illness, according to Cynthia Delgado, MD, associate professor of medicine at the San Francisco Veterans Affairs Medical Center and University of California San Francisco Medical Center.
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January 21st 2020

Bundled Payments: Looking Back, Looking Ahead

Alyssa Dahl, MPH
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November 13th 2019

National Kidney Foundation: New Study Suggests Intervention for Kidney Disease Can Reduce Hospitalizations and Costs

National Kidney Foundation and CareFirst partnered for the first time on landmark study
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November 10th 2019

Physicians, Patient Discuss Intentional Nonadherence in Hypertension Therapy

Allison Inserro
What should providers do about intentional nonadherence, and what strategies should they try to get their patients to take their hypertension medicine? At a session at the American Society of Nephrology (ASN)’s Kidney Week 2019, physicians discussed direct observation therapy (DOT), drug monitoring, case studies, and other published work about patients who don’t take their medications. Then they heard from a directly from a patient who shared why she stopped taking her medication and the scary consequence that developed as a result.
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November 8th 2019

CKD Quality Improvement Intervention With PCMH Integration: Health Plan Results

Joseph A. Vassalotti, MD Rachel DeVinney, MPH, CHES Stacey Lukasik, BA Sandra McNaney, BS Elizabeth Montgomery, BS Cindy Voss, MA Daniel Winn, MD
A scalable chronic kidney disease (CKD) quality improvement intervention demonstrated feasibility, decreased hospitalization, and reduced costs. These preliminary results support innovation in CKD by commercial health plans.
Dr Danielle Kirkman Explains How Exercise Testing in Patients With CKD Can Improve Care
November 8th 2019

Dr Danielle Kirkman Explains How Exercise Testing in Patients With CKD Can Improve Care

Because exercise capacity is known to be linked with several key outcome measures in patients with chronic kidney disease (CKD), routine exercise testing can help clinicians prescribe individualized exercise interventions, said Danielle Kirkman, PhD, assistant professor at Virginia Commonwealth University.
FDA Approves Canagliflozin to Prevent Kidney Failure, Hospitalization for Heart Failure
October 1st 2019

FDA Approves Canagliflozin to Prevent Kidney Failure, Hospitalization for Heart Failure

Mary Caffrey
The new indication is based on results of the CREDENCE trial, which found that canagliflozin reduced the risk of renal failure or death by 30% in those that had both type 2 diabetes and diabetic kidney disease.
FDA Grants Fast Track Designation for Dapagliflozin to Prevent Kidney Failure
August 27th 2019

FDA Grants Fast Track Designation for Dapagliflozin to Prevent Kidney Failure

Matthew Gavidia
Dapagliflozin’s fast track designation follows findings from last year’s DECLARE-TIMI trial, a cardiovascular outcomes trial that showed the drug’s significant impact on delaying the loss of kidney function and reducing hospitalization risk for heart failure.
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June 30th 2019

2019 ADA Coverage: Renal Outcomes

Mary Caffrey
Coverage of DECLARE, CARMELINA, and other studies that highlight the connection between diabetes and renal outcomes
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