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In the majority of the 49 patients with a type of spinal muscular atrophy called spinal muscular atrophy Jokela, creatine kinase was elevated, particularly in males.

Assessing the presence of vascular endothelial growth factor (VEGF) in tears could be a noninvasive way to determine the severity and progression of age-related macular degeneration.

The phase 3 trial of valoctocogene roxaparvovec for severe hemophilia A showed it reduced bleeding events as well as the use of factor VIII concentrates.

Pfizer and BioNTech requested FDA emergency use authorization for a fourth COVID-19 dose for older adults; postpartum depression rates tripled during early months of the COVID-19 pandemic; anxiety and depression diagnoses among children each increased by roughly 25% since 2016.

According to a recent review, digital technology can be used for COPD self-management, learning correct inhaler technique, and receiving care from health care professionals.

FDA issued a complete response letter (CRL) to AstraZeneca seeking additional clinical data for benralizumab, sold as Fasenra, in the treatment of patients with inadequately controlled chronic rhinosinusitis with nasal polyps.

The genetically-predicted risk of rheumatoid arthritis (RA) was positively associated with an increased risk of inflammatory bowel disease (IBD) and potentially with its main subtypes, ulcerative colitis and Crohn disease.

Genome sequencing of tumors from children and adolescents with recurrent or refractory cancer led to over 100 patients receiving targeted therapies.

Full approval by the FDA follows tentative approval for the complex drug delivery advice for asthma and chronic obstructive pulmonary disease (COPD) granted by the FDA last week amid a patent dispute.

Finerenone (Kerendia) was found to reduce risk of heart failure and improve other cardiovascular outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) regardless of heart failure history.

Findings of a meta-analysis suggest adding antiangiogenics to second-line treatment in non–small cell lung cancer (NSCLC) may improve survival outcomes, especially in younger patients.

Jill Hutt, vice president of member services at the Greater Philadelphia Business Coalition on Health (GPBCH), explains why it is cost effective for employers to address employees' prediabetes.

A survey done by ResMed found that poor sleep quality was linked to depression, anxiety, and stress brought on by the pandemic.

Idaho legislature passed Texas-inspired abortion law banning the procedure after 6 weeks of pregnancy; patients who were bedridden with severe cases of COVID-19 had increased risks of anxiety and depression more than a year later; number of deaths by suicide in Japanese women rose for second straight year.

Longer-term findings of the Measure Up 1 and 2 studies showed the JAK inhibitor upadacitinib to be safe and effective after 52 weeks in the treatment of adults and adolescents with moderate to severe atopic dermatitis.

Ron Do, PhD, associate professor, Charles Bronfman Institute for Personalized Medicine at Mount Sinai, and Iain Forrest, MD-PhD candidate in Dr Do’s lab, discuss their hopes for their findings and how genetic data are being used in health care.

Researchers outlined trends in treatment and management for patients presenting to the emergency department with headaches.

A recent study found that an electronic tool that guides diagnosis and treatment can reduce mortality and improve processes of care.

Authors from the Community Oncology Alliance and Avalere Health present data that show breast cancer screening rates recovered more slowly among some racial/ethnic groups following on the onset of the COVID-19 pandemic.

Cardiac troponin I (cTnI) and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) were associated with incident cardiovascular events in patients with psoriatic disease.

The FDA based its approval on OlympiA trial data, which show the PARP inhibitor has the ability to reduce risks of invasive breast cancer recurrence, second cancers, and death, and to improve overall survival.

Screening for colorectal cancer is an urgent priority for Americans aged 45 and older; low COVID-19 vaccine uptake was observed among US children aged 5 to 11 years in the first weeks of eligibility; WHO warns of increased alcohol consumption risk due to the pandemic.

As the United States awaits market introduction for adalimumab biosimilars in 2023, 2022 is going to be the year of expanding access to biosimilars, according to Julie M. Reed, the new executive director of the Biosimilars Forum.

The first in-person Community Oncology Alliance (COA) meeting in 2 years will feature sessions on practice management, health disparities, and more. A virtual option is available.

Kashyap Patel, MD, chief executive officer, Carolina Blood and Cancer Care Associations, and current president of the Community Oncology Alliance (COA), previews his discussion on health equity to be held at the 2022 Community Oncology Conference.

Patients with chronic rhinosinusitis (CRS) with severe radiographic disease were more likely to report incidence of nasal polyps and be managed by endoscopic sinus surgery, but did not show greater health care utilization.

Patients with polycythemia vera (PV) or essential thrombocythemia (ET) had a higher risk of thrombotic events than the general population, which was associated with mortality in a recent study.

Among patients with atopic dermatitis, the risk and severity of acne varied based on age and sex.