Clinical

A study of patients with severe chronic obstructive pulmonary disease (COPD) in Poland, The Republic of Korea, and the United States identified substantial differences in respiratory symptoms and other respiratory illnesses.

Sanofi’s newest insulin met its primary objective in a large head-to-head trial that compared it with its chief competitor.

The National Cancer Institute (NCI) is sponsoring an ongoing clinical trial that evaluates pembrolizumab in people with HIV who have relapsed or refractory cancer and are also taking antiretroviral therapy. People with HIV are often excluded from participating in clinical trials of new cancer treatments because of concerns that treatments may be unsafe for them.

With the increasing emergence of less expensive biologic alternatives, some health systems are making the switch. For a large healthcare system, the arrival of a cheaper alternative to filgrastim prompted the conversion to using tbo-filgrastim as the preferrred granulocyte-colony stimulating factor. The results were shared in a study published by the Journal of Managed Care & Specialty Pharmacy.

Brain magnetic resonance imaging (MRI) can be used to identify people with attention-deficit/hyperactivity disorder from patients without the condition, according to a new study.

A look at the millions of tax filers who chose the penalty over insurance coverage; the cost of unnecessary or excessively expensive medical care; Takeda begins the first Zika vaccine trial.

Patients are significantly overestimating the pain they will feel after surgery, indicating that providers can do a better job of educating patients on what they can expect.

A non-fasting test to measure low-density lipoprotein (LDL) cholesterol has many advantages for patients and physicians, but payers can also see some benefits, explained Eliot A. Brinton, MD, FAHA, FNLA, president of the Utah Lipid Center.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Chemotherapy and radiation therapy should be the first line of treatment for certain prostate cancers and lymphomas with a major genetic weakness, according to researchers at the University of Virginia School of Medicine.

VA Secretary David Shulkin wants the private sector to play a larger role in veterans' healthcare; Arizona's Supreme Court ruled in favor of a component to keep the state's Medicaid expansion; Acorda ends drug development of tozadenant for Parkinson's disease.

Most US adults would prefer to find other ways to manage their pain, such as neck or back pain, before taking prescribed pain medication, a Gallup research brief found.