The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.
May 1st 2025
Patients with neovascular age-related macular degeneration (nAMD) experienced improvements in central macular thickness and subretinal and intraretinal fluid after switching.
Analysis of COPD Hospitalization Trends Finds Gender Gap for Mortality
June 20th 2017With more women dying annually from chronic obstructive pulmonary disease (COPD) than men since 2000, researchers have examined trends in COPD hospitalization and in-hospital mortality, evaluating for differences by sex and race. They presented their research at the American Thoracic Society 2017 International Conference.
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Diagnostic Test Brings a Precision Medicine Approach to Prostate Cancer Drug
June 19th 2017A collaborative study among scientists working across 3 continents has found a strong association between circulating free DNA in patients being treated with olaparib (Lynparza) for prostate cancer and disease outcome.
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Dr Scott Ramsey on Challenges of Determining Cost Effectiveness of Novel Cancer Treatments
June 19th 2017Scott Ramsey, MD, PhD, of Fred Hutchinson Cancer Research Center, discusses determining cost effectiveness of novel treatments, such as immuno-oncology agents, and potential solutions to reducing financial toxicity in cancer care.
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WCHN Launches New Study to Investigate Link Between Diabetes and Pancreatic Cancer
June 14th 2017On June 14, 2017, Western Connecticut Health Network (WCHN) announced its launch of a new study that will research the connection between pancreatic cancer and new-onset diabetes. This $2.7 million study will span 3 years and aims to discover a method to detect pancreatic cancer while it can still be cured.
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Genome-Wide Association Studies Identify Novel Risk Loci for Testicular Cancer
June 14th 2017A meta-analysis spearheaded by The International Testicular Cancer Consortium has identified new susceptibility loci in the human genome that can increase a person’s risk of developing inherited testicular germ cell tumors.
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Real-World Treatment Patterns Highlight Need for Clinical Education on PD-L1 Testing in NSCLC
June 13th 2017Data presented by the FDA at the 2017 American Society of Clinical Oncology Annual Meeting identified a need for educating community-based oncology practices on testing for programmed death-ligand 1 (PD-L1) protein expression before patients diagnosed with metastatic non-small cell lung cancer (mNSCLC) are treated with nivolumab or pembrolizumab.
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NEJM Study Oncologists: Do Small Breast Cancers Indicate Overdiagnosis?
June 8th 2017A new study analyzing breast cancer data in the SEER database has concluded that small tumors detected following a mammography might be small because they are slow-growing, and not necessarily because they were detected early.
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Phase 1 Study Results at ASCO Support First-Line Use of Daratumumab in Multiple Myeloma
June 7th 2017A phase 1 study, presented at the 2017 American Society of Clinical Oncology Annual Meeting, found that including daratumumab can improve patient response to treatment in newly diagnosed multiple myeloma.
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NCI-Sponsored Cancer Trials Potentially Saved Millions of Life-Years, Study Finds
June 7th 2017A new study estimates that the cooperative research network SWOG, which is sponsored by the National Cancer Institute (NCI), has considerably impacted the US population over its 60-year history, as its 23 positive clinical trials have generated about 3.34 million life-years gained.
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Daratumumab With Standard Regimen Improves PFS in Multiple Myeloma, Independent of Cytogenetic Risk
June 5th 2017Updated results from the POLLUX and CASTOR trials, presented at the 2017 American Society of Clinical Oncology Annual Meeting, have found that including daratumumab in standard-of-care regimens prolonged progression-free survival (PFS) and improved the depth of response, independent of the patients’ cytogenetic risk.
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Dr Craig Portell Highlights New and Exciting Treatments for Non-Hodgkin's Lymphoma
June 5th 2017Craig Portell, MD, of the University of Virginia Health System, highlights some of the latest and most exciting treatments in non-Hodgkin's lymphoma, including CAR-T therapies and targeted therapies such as venetoclax.
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Dr Edward Li Discusses the Benefit Biosimilars Can Have in Oncology
June 4th 2017The impact that generics have on bringing down the cost of branded drugs needs to happen in the biologics space so the industry can save money and improve access to medications and population outcomes, according to Edward Li, PharmD, MPH, BCOP, of the University of New England.
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Switching Study Reports Equivalence Between Filgrastim, Biosimilar in Breast Cancer
June 4th 2017A phase 3, randomized, double-blind registration study in patients with breast cancer receiving neoadjuvant myelosuppressive chemotherapy has found clinical equivalence between filgrastim and its biosimilar after switching studies.
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Do We Have Adequate Surveillance in Cancer Survivor Care?
June 4th 2017A poster discussion session at the 2017 Annual Meeting of the American Society of Clinical Oncology examined retrospective surveillance data in 3 different cancers: non-small cell lung cancer, head and neck cancer, and colorectal cancer.
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Physician, Regulatory, and Payer Perspectives on the Value of Real-World Data
June 3rd 2017One of the kickoff sessions on the first day of the 2017 American Society of Clinical Oncology Annual Meeting in Chicago, Illinois, was a lively discussion on ensuring that the data used to inform patient care and create healthcare policies holds value.
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Patient Selection Vital in Ensuring Improved Response to PD-1, PD-L1 Inhibitors in NSCLC
June 3rd 2017A late afternoon extended education session on the first day of the 2017 American Society of Clinical Oncology Annual Meeting in Chicago, Illinois, was a discussion on the state-of-the-art uses for immunotherapy in the management of non-small cell lung cancer (NSCLC).
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Dr Daniel George Highlights Successes of Checkpoint Inhibitors in Prostate, Bladder Cancers
June 3rd 2017Checkpoint inhibitors have begun to revolutionize bladder cancer treatments, but the benefits in prostate cancer are a little less clear at this point, explained Daniel George, MD, of the Duke Cancer Insitute.
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