
Opinion|Videos|May 12, 2025
Applying Trial Data to Real-World Practice in ALK+ NSCLC
Panelists discuss how clinical trial outcomes like CROWN and eXalt3 reflect real-world patient experiences and how these collective data have changed perspectives on frontline therapies for ALK+ non–small cell lung cancer (NSCLC).
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Episodes in this series

Real-World Settings and Evolution of Frontline Therapy
Key Themes:
- Comparison of clinical trial outcomes to real-world patient experiences
- Impact of clinical data (ALINA, CROWN, eXalt3) on frontline therapy choices
- Evolving perspective on frontline therapies for ALK+ NSCLC
Notable Insights:
- Grizzard addressed how well outcomes from trials like CROWN and eXalt3 reflect real-world patient experiences
Dr Dietrich summarized how recent clinical data has changed the landscape of frontline therapies for ALK+ NSCLC
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