Opinion|Videos|May 19, 2025

Key Differences Among ALK Inhibitors

Panelists discuss how currently available ALK inhibitors compare in terms of efficacy, durability of response, and central nervous system (CNS) penetration for metastatic non–small cell lung cancer treatment.

ALK Inhibitor Comparison and CNS Penetration

Key Themes:

  • Overview of currently available ALK inhibitors in the metastatic setting
  • Comparative analysis of efficacy and durability of response
  • Differences in CNS penetration among ALK inhibitors

Notable Insights:

  • Dr Lovly provided a comprehensive overview of available ALK inhibitors and their comparative efficacy

Dr Dietrich highlighted clinically relevant differences in CNS penetration and their influence on therapy selection

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